کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7887656 | 1509791 | 2018 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis and characterisation of nanophase hydroxyapatite co-substituted with strontium and zinc
ترجمه فارسی عنوان
سنتز و مشخصه هیدروکسی آپاتیت نانوفاز مشترک با استرانتیوم و روی
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
سرامیک و کامپوزیت
چکیده انگلیسی
In order to develop new bioactive calcium phosphate (CaP) materials to repair bone defects, it is important to ensure these materials more closely mimic the non-stoichiometric nature of biological hydroxyapatite (HA). Typically, biological HA combines various CaP phases with different impurity ions, which substitute within the HA lattice, including strontium (Sr2+), zinc (Zn2+), magnesium (Mg2+), carbonate (CO32-) and fluoride (F-), but to name a few. In addition to this biological HA have dimensions in the nanometre (nm) range, usually 60â¯nm in length by 5-20â¯nm wide. Both the effects of ion substitution and the nano-size crystals are seen as important factors for enhancing their potential biofunctionality. The driving hypothesis was to successfully synthesise nanoscale hydroxyapatite (nHA), co-substituted with strontium (Sr2+) and zinc (Zn2+) ions in varying concentrations using an aqueous precipitation method and to understand their chemical and physical properties. The materials were characterised using Fourier Transform Infrared Spectroscopy (FTIR), X-Ray Diffraction (XRD), X-Ray Photoelectron Spectroscopy (XPS) and Transmission Electron Microscopy (TEM) techniques. The FTIR, XRD and XPS results confirmed that the nHA was successfully co-substituted with Sr2+ and Zn2+, replacing Ca2+ within the nHA lattice at varying concentrations. The FTIR results confirmed that all of the samples were carbonated, with a significant loss of hydroxylation as a consequence of the incorporation of Sr2+ and Zn2+ into the nHA lattice. The TEM results showed that each sample produced was nano-sized, with the Sr/Zn-10%nHA having the smallest sized crystals approximately 17.6 ± 3.3â¯nm long and 10.2 ± 1.4â¯nm wide. None of the materials synthesised here in this study contained any other impurity CaP phases. Therefore, this study has shown that co-substituted nHA can be prepared, and that the degree of substitution (and the substituting ion) can have a profound effect on the attendant materials' properties.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ceramics International - Volume 44, Issue 7, May 2018, Pages 7761-7770
Journal: Ceramics International - Volume 44, Issue 7, May 2018, Pages 7761-7770
نویسندگان
N. Lowry, M. Brolly, Y. Han, S. McKillop, B.J. Meenan, A.R. Boyd,