کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7898555 | 1510138 | 2018 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Femtosecond laser multi-patterning of zirconia for screening of cell-surface interactions
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کلمات کلیدی
FIBhMSCWLI3Y-TZPWhite light interferometry - interferometry سفید سفیدPattern - الگوFocused ion beam - باریکه یونی متمرکز یا بیمlow temperature degradation - تخریب دما پایینTopography - توپوگرافیZirconia - زیرکونیاSurface - سطحیhuman mesenchymal stem cells - سلول های بنیادی مزانشیمی انسانیLaser - لیزرLTD - محدودSEM - مدل معادلات ساختاری / میکروسکوپ الکترونی روبشیScanning electron microscopy - میکروسکوپ الکترونی روبشی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
سرامیک و کامپوزیت
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
Yttria-stabilised tetragonal zirconia polycrystals (3Y-TZP) bioinert ceramics combine excellent strength and toughness, good aesthetics, high resistance to corrosion and absence of allergic reaction. However, improved osseointegration is needed as higher marginal bone loss was sometimes reported. In the present work, 3Y-TZP multi-patterned samples for rapid screening of cell-surface interactions were fabricated by femtosecond laser micromachining. Pits with well-defined edges and micrometric precision in pit diameter, depth and spacing were produced, as determined by white light interferometry. Pits showed a nanometric granular texture on the sidewalls and ripples at pit bottom, as attested by scanning electron microscopy. Focused ion beam analyses indicated limited laser-induced damage. Micropatterns impacted human mesenchymal stem cell (hMSC) size and morphology. Cell area and aspect ratio were mainly influenced by pit diameter, while solidity and circularity were affected by both pit diameter and depth. The pattern 30 μm diameter/10 μm depth induced the strongest osteoblastic hMSC commitment.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the European Ceramic Society - Volume 38, Issue 3, March 2018, Pages 939-948
Journal: Journal of the European Ceramic Society - Volume 38, Issue 3, March 2018, Pages 939-948
نویسندگان
Ana-Maria Stanciuc, Quentin Flamant, Christoph Martin Sprecher, Mauro Alini, Marc Anglada, Marianna Peroglio,