کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8012708 | 1517161 | 2018 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Electrospun scaffolds with enlarged pore size: Porosimetry analysis
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
فناوری نانو (نانو تکنولوژی)
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Electrospun polymeric/composite scaffolds exhibit a micro/nanofibrous structure that resembles the architecture of native extracellular matrix. The unique properties of the interconnected pores and high porosity of electrospun matrices make them very attractive for applications in tissue engineering scaffolding. However, these structures are formed by densely compacted fibers that exhibit pore sizes lower than cell size, leading to poor cell infiltration. In this work, bead-free electrospun poly(ε-caprolactone) fibrous scaffolds were prepared by combining electrospinning and salt-leaching techniques. Non-woven scaffolds were obtained using porogens with different sizes. Liquid extrusion porosimetry was used to accurately determine pore size and its distribution. The structural features of prepared matrices were dependent on the initial porogen size but resulted much smaller than this one.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Letters - Volume 227, 15 September 2018, Pages 191-193
Journal: Materials Letters - Volume 227, 15 September 2018, Pages 191-193
نویسندگان
Pablo R. Cortez Tornello, Pablo C. Caracciolo, Juan I. Igartúa Roselló, Gustavo A. Abraham,