کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8015880 1517203 2016 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Mechanical stability of highly porous hydroxyapatite scaffolds during different stages of in vitro studies
ترجمه فارسی عنوان
پایداری مکانیکی داربست های هیدروکسی آپاتیت بسیار متخلخل در مراحل مختلف مطالعات آزمایشگاهی
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد فناوری نانو (نانو تکنولوژی)
چکیده انگلیسی
Degradation properties of bone scaffolds are strongly related to cell growth, host response and tissue regeneration. However, bone formation is a very slow process and, in the first few weeks after implantation, the mechanical stability of the scaffold plays a key role for the success of the regeneration progression. In the present study, in vitro properties of highly porous hydroxyapatite (HA) scaffolds were analysed in terms of bioactivity and biodegradation by observing their microstructure, measuring the weight loss and evaluating their mechanical stability. HA scaffolds fabricated by sponge replica method have been incubated for different periods of time in Simulated Body Fluid and in tris-HCL buffer. The morphological and mechanical characterizations performed on the scaffolds before and after immersion demonstrated the scaffolds being bioactive and almost not biodegradable in four weeks in terms of weight loss and mechanical resistance.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Letters - Volume 185, 15 December 2016, Pages 239-242
نویسندگان
, , , , ,