کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8017022 1517210 2016 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Comparison of in vitro biocompatibility of a Co-Cr dental alloy produced by new milling/post-sintering or traditional casting technique
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد فناوری نانو (نانو تکنولوژی)
پیش نمایش صفحه اول مقاله
Comparison of in vitro biocompatibility of a Co-Cr dental alloy produced by new milling/post-sintering or traditional casting technique
چکیده انگلیسی
The purpose of this study was to evaluate metal ion release of a cobalt-chromium (Co-Cr) alloy produced by using both the new milling/post-sintering (MPS) and traditional casting (CAST) techniques and the influence of ion release on cell response. The concentration of released ions from the specimens immersed in artificial saliva (pH 5.3 and 2.3) and cell culture medium was measured by inductively coupled plasma-mass spectroscopy. Cell (L929 mouse fibroblasts) response to the specimens was evaluated by water-soluble tetrazolium salt-8 assay (1, 3, and 7 days). The microstructure of the MPS specimen was characterized by fine grain size and predominant ε (hexagonal close-packed) phase. The MPS specimens showed consistently significantly smaller releases of Co ions than the CAST specimens (P<0.05) regardless of the immersion solutions used. Although the cell morphology was normal in both groups, cell viability was consistently significantly higher in the MPS group than in the CAST group (P<0.05). These findings suggest that the MPS-fabricated Co-Cr alloy showed better in vitro biocompatibility than the cast one.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Letters - Volume 178, 1 September 2016, Pages 300-303
نویسندگان
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