کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8017200 | 1517215 | 2016 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Aqueous synthesis of CuInZnS/ZnS quantum dots by using dual stabilizers: A targeting nanoprobe for cell imaging
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
فناوری نانو (نانو تکنولوژی)
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
Herein, we prepared dual-stabilizer-capped CuInZnS/ZnS (CIZS/ZnS) quantum dots (QDs) in aqueous media via hydrothermal routes. On using the combination of poly (styrenesulfonic acid-co maleic acid) and glutathione stabilizers, we found that dual stabilizers effectively coat the surface of CIZS/ZnS QDs, resulting in high quantum yields and carboxylic acid groups that conjugate with various materials. To demonstrate their potential biomedical application, the dual-stabilizer-capped CIZS/ZnS QDs were conjugated with 3-aminophenylboronic acid, termed CIZS/ZnS@APBA, for HeLa tumor cell labeling. In vitro and in vivo assessments using HeLa cells and zebrafish embryos, respectively, revealed that these CIZS/ZnS@APBA nanoprobes exhibit low cytotoxicity under our experimental conditions. Confocal scanning laser imaging demonstrated that the nanoprobes can be efficiently internalized and are localized in the cytoplasm of HeLa cells. This work reveals the potential for use of CIZS/ZnS@APBA as a safe and effective targeted probe for in vivo imaging of cancer.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Letters - Volume 173, 15 June 2016, Pages 242-247
Journal: Materials Letters - Volume 173, 15 June 2016, Pages 242-247
نویسندگان
Jayaraman Vinayagam, Guan-Rong Chen, Ting-Yi Huang, Jinn-Hsuan Ho, Yong-Chien Ling, Keng-Liang Ou, Jia-Yaw Chang,