Synthesis of porous CaTiO3 nanotubes with tunable hollow structures via single-nozzle electrospinning

The synthesis of porous CaTiO3 (CTO) nanotubes with controlled microstructure was demonstrated via a single-nozzle electrospinning approach. Homogenous sols comprising polyvinylpyrolidine (PVP), Pluronic F127 and CTO (metal salt) were electrospun, which resulted in fine CTO nanotubes due to phase separation phenomenon. PVP/CTO molar ratio was confirmed to induce the effective manipulation of its structural characteristics. Altering the ratio from 0.24 m to 0.12 m was found to result in the increased fiber diameter, from ~105 nm to ~230 nm, and the enhanced hollow structure (diameter of ~70 nm). Further development of biocompatible inorganic CaTiO3 nanotubes with such tunable hollow structures provides a platform for sustained drug loading and delivery.