Synthesis and enhanced electrochemical property of Au-doped cerium phosphate nanowires

Au-doped cerium phosphate (Au/CePO4) nanowires (NWs) were prepared through combining hydrothermal and solvothermal methods, in which Au NP sizes and numbers could be tailored through varying chloroauric acid concentrations. The Au/CePO4 NWs were utilized to explore a novel biosensor through coupling hemoglobin (Hb) with chitosan (Chi). Compared with Hb-Chi-CePO4/GC electrode, Hb-Chi-Au/CePO4/GC electrode exhibited a pair of much stronger redox peaks at −0.32 V. Moreover, the electrochemical properties of the Au/CePO4-based biosensors closely depended on their Au NP sizes and numbers. The Au(2)/CePO4-constructed biosensor had the most excellent electrochemical properties in comparison with CePO4- and other Au(x)/CePO4-constructed biosensors.