Production and purification of Scandium-47: A potential radioisotope for cancer theranostics

In this study, production of 47Sc radionuclide by irradiating the natural titanium dioxide powder (TiO2) in the fast neutron flux (~3*1013 n cm−2 s−1) for 4 days in Tehran Research Reactor (TRR, Iran) and separation from titanium target was investigated. The study showed the feasibility of production 47Sc by TRR. The separation efficiency and radiochemical purity (ScCl3) of radio-scandium, 47Sc radionuclide purity were obtained 98%, 99% and 88% respectively.