Aged-related increase of high sensitive Troponin T and its implication in acute myocardial infarction diagnosis of elderly patients

► Healthy reference population ranging from 50 to 105 years old were enrolled. ► An age-related increase of hs-cTnT levels was observed in the reference population. ► Geriatric patients (>75 and <96 years old) suspected of having an AMI were enrolled. ► The hs-cTnT cut-off value in geriatric patients is different from that currently recommended. ► hs-cTnT cut-off value must be tailored to the age of patients with a suspected AMI.