Plasmodium falciparum Prp16 homologue and its role in splicing

► mRNA splicing and splicing factors are not well understood in P. Falciparum. ► Biochemical and functional characterization of an important splicing factor, PfPrp16. ► PfPrp16 acts at second step of splicing. ► Biochemical properties of PfPrp16 may be modulated by its C-terminal region. ► Study will facilitate understanding of RNA splicing machinery in P. Falciparum.