Overexpression and clinical significance of carcinoembryonic antigen-related cell adhesion molecule 6 in colorectal cancer

► CEACAM6 levels are increased in human tumor tissues compared to non-tumor regions. ► CEACAM6 is correlated with clinicopathologic features and survival rate. ► CEACAM6 levels promote invasiveness in colorectal cancer cell lines. ► CEACAM6 plays an important role in tumorigenesis and acquisition of invasiveness.