Limitations in qualitative point of care hCG tests for detecting early pregnancy

► Qualitative detection of hCG in urine is a high volume test. ► A low incidence of false negative POC hCG results can impact patients. ► We evaluated two POC hCG tests for the detection of hCG at concentrations < 300 IU/l. ► Our results reveal limitations in POC devices for detecting early pregnancy.