Chimerism analysis in transplant patients: A hypothesis-free approach in the absence of reference genotypes

► An algorithm to determine the chimerism in transplant patients was built. ► It is based in the study of a group of STR loci. ► It can be applied when the donor and/or recipient genetic profiles are unknown. ► The predicted values were closely correlated (r2 > 0.98) with the reference values. ► It can be a useful tool for laboratories involved in chimerism analysis.