Characteristics and prevalence of KRAS, BRAF, and PIK3CA mutations in colorectal cancer by high-resolution melting analysis in Taiwanese population

► We investigate the occurrence of KRAS, BRAF, and PIK3CA mutations in the Taiwanese population with colorectal cancer. ► We report that the frequency of KRAS, BRAF and PIK3CA mutations is 33.5%, 1.1%, and 7.1%, respectively. ► HRM analysis is a feasible diagnostic tool for the detection of BRAF and PIK3CA mutations.