Analysis of human glutathione S-transferase alpha 1 (hGSTA1) gene promoter polymorphism using Denaturing High Performance Liquid Chromatography (DHPLC)

From the total of 117 samples, 43.5% are homozygous for hGSTA1*A allele, 13% are homozygous for hGSTA1*B allele and 43.5% are hGSTA1*A/B heterozygotes. This is, to our knowledge, the first report on the use of DHPLC for the evaluation of hGSTA1 gene promoter polymorphism.