Reference values for serum levels of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in Korean children and adolescents

► We measured serum IGF-I and IGFBP-3 in 1378 healthy Korean children and adolescents. ► We established reference values based on age, sex, and pubertal stage. ► Our reference value model can improve the diagnostic utility of IGF-I and IGFBP-3.