More pieces to the puzzle: recent structural insights into class II transcription initiation

- Cryo-EM structures illuminate human TFIID plasticity.
- TAF1-TBP crystal structure reveals regulatory roles of TAF1 in transcription.
- RNAPII-TFIIB initially transcribing complex (ITC) structure details TFIIB function.
- Crystal structures of the Mediator head module were elucidated.
- EM studies reveal principles of yeast and human PIC assembly.