LAT1 is the transport competent unit of the LAT1/CD98 heterodimeric amino acid transporter

- [3H]His transport was measured in intact SiHa and in proteoliposomes.
- Cleavage of disulfide between CD98 and LAT1 did not modify transport properties.
- Transport in proteoliposomes reconstituted with the sole hLAT1 confirmed data.
- Therefore, LAT1 is the sole transport competent unit of the heterodimer.