Reduced inflammatory activity of RAW 264.7 macrophages on titania nanotube modified Ti surface

- TiO2 nanotubes with 78 nm diameter were elaborated by electrochemical anodization.
- Macrophage activation was alleviated by TiO2 nanotube surface as compared to pure Ti.
- TiO2 nanotubes lowered expression of pro-inflammatory molecules in RAW 264.7 cells.
- TiO2 nanotubes decreased secretion of pro-inflammatory cytokines/chemokines and NO.
- LPS treatment of macrophages induced less FBGCs on TiO2 nanotubes than on pure Ti.