Osmotic stress transcription factor 1b (Ostf1b) promotes migration properties with the modulation of epithelial mesenchymal transition (EMT) phenotype in human embryonic kidney cell

- Ostf1b stimulates cell migration with modulation of EMT phenotype.
- It activates ROCK1 and MLC2 in RhoA signalling pathway.
- It induces protein expression of two tight junction proteins.
- It stimulates the formation of actin fibre.