Virus-induced changes in mitochondrial bioenergetics as potential targets for therapy

► Viral biogenesis depends on energy and metabolic resources provided by the host. ► Mitochondrial bioenergetics is modulated by viral replication. ► Mitochondrial ATP production, apoptosis, innate immune responses are mitochondrial functions modulated by viral infections. ► Metabolic antagonists may help understand the pathogenesis of viral diseases.