کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8329326 | 1540209 | 2018 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
β-d-glucan as an enteric delivery vehicle for probiotics
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
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چکیده انگلیسی
Three strains of probiotics L. casei, L. acidophilus and B. bifidum were encapsulated in β-d-glucan matrix using freeze drying technique in order to increase survivability during their journey through GI tract. The encapsulation efficiency (%) of β-d-glucan varied significantly with Bifidobacteria showing low survival rate than Lactobacilli. SEM images revealed a partially collapsed structure with bacterial cells distributed randomly in the matrix. Further absorption band between 1300 and 900 cmâ1 in FTIR spectra shows the presence of bacterial proteins and nucleic acids. For encapsulated β-d-glucan maximum degree of swelling was observed at pH 3 and 4, whereas when the pH value was increased to 6.5 the encapsulated β-d-glucan started their disintegration. In vitro release studies revealed that the microcapsules start to dissolve upon entry to the small intestine where it is needed most.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Biological Macromolecules - Volume 106, January 2018, Pages 864-869
Journal: International Journal of Biological Macromolecules - Volume 106, January 2018, Pages 864-869
نویسندگان
Adil Gani, Asima Shah, Mudasir Ahmad, Bilal Ahmad Ashwar, F.A. Masoodi,