کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8333892 | 1540266 | 2013 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
HIV-1 and HSV-1 virus activities of some new polycyclic nucleoside pyrene candidates
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: HIV-1 and HSV-1 virus activities of some new polycyclic nucleoside pyrene candidates HIV-1 and HSV-1 virus activities of some new polycyclic nucleoside pyrene candidates](/preview/png/8333892.png)
چکیده انگلیسی
In continuation of our previous work, a novel series of polycyclic derivatives 2-8 incorporated heterocyclic and sugar moieties were synthesized by using pyren-1-aldehyde (1) as starting material and their tested as antiviral activities. Initially, the toxicity of the compounds was assayed via the determination of their EC50. Some of the synthesized compounds were tested as antiviral activity against HIV-1 and HSV-1. The structure of the new compounds was confirmed by using chemical and spectroscopic evidences. The detailed of synthesis, spectroscopic data, antiviral activities of the synthesized compounds were reported.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Biological Macromolecules - Volume 54, March 2013, Pages 51-56
Journal: International Journal of Biological Macromolecules - Volume 54, March 2013, Pages 51-56
نویسندگان
Nagy M. Khalifa, Mohamed A. Al-Omar, Abd El-Galil E. Amr, Mogedda E. Haiba,