Keywords: آنالوگهای هسته ای; Dengue fever; Anti-DENV; Nucleoside analogs;
مقالات ISI آنالوگهای هسته ای (ترجمه نشده)
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Keywords: آنالوگهای هسته ای; Equine; Herpesvirus; EHV-1; EHV-5; Antiviral; Nucleoside analogs; Acyclovir; Valacyclovir;
Keywords: آنالوگهای هسته ای; Nucleoside transporters; Transportome; Digestive/gastrointestinal tumors; Network; Nucleoside analogs;
Keywords: آنالوگهای هسته ای; Boron clusters; Nucleoside analogs; Antiviral activity; HCMVOIEKATGVWVSPSQ-SGJXDDMKSA-N
Keywords: آنالوگهای هسته ای; Nucleoside analogs; Dengue virus; Antiviral therapy; Monophosphate prodrug;
Keywords: آنالوگهای هسته ای; Thymidine kinase 2; Deoxyguanosine kinase; Nucleoside analogs; ddI; Mitochondrial toxicity;
Keywords: آنالوگهای هسته ای; Dynamic chemistry; Dynamic kinetic resolution; Enzyme catalysis; Hemithioacetal formation; Lactonization; Nucleoside analogs; SHFSVYJFBUSHGX-UHFFFAOYSA-N; SJMAXYQDASOPCT-UHFFFAOYSA-N; RSLWYWHVRGRLGW-UHFFFAOYSA-N; CGYMNXMAUZMIJL-UHFFFAOYSA-N; SDAJIOQLJUVSN
Keywords: آنالوگهای هسته ای; Thiols; Nucleophilic aromatic substitution; Nucleoside analogs; Purine derivatives;
Keywords: آنالوگهای هسته ای; Nucleoside analogs; Antiviral; Anticancer; Phosphorodiamidates; Prodrugs;
Synthesis of novel 6-substituted amino-9-(β-d-ribofuranosyl)purine analogs and their bioactivities on human epithelial cancer cells
Keywords: آنالوگهای هسته ای; Nucleoside analogs; Microwave-assisted synthesis; Cytotoxic activity; Hepatocellular carcinoma;
Recovery of circulating CD56dim NK cells and the balance of Th17/Treg after nucleoside analog therapy in patients with chronic hepatitis B and low levels of HBsAg
Keywords: آنالوگهای هسته ای; Hepatitis B virus; Nucleoside analogs; Natural killer cells; Regulatory T cells; T-helper cells;
Simultaneous quantification of intracellular lamivudine and abacavir triphosphate metabolites by LC-MS/MS
Keywords: آنالوگهای هسته ای; Triphosphate metabolites; LC-MS/MS; Nucleoside analogs; Mice;
Systematic review with meta-analysis: Change in liver stiffness during anti-viral therapy in patients with hepatitis B
Keywords: آنالوگهای هسته ای; Fibrosis; Nucleoside analogs; Treatment success; Viral suppression;
Nucleosidic DNA demethylating epigenetic drugs - A comprehensive review from discovery to clinic
Keywords: آنالوگهای هسته ای; ALL; Acute lymphoblastic leukemia; AML; Acute myeloid leukemia; AUC; Area under the curve; AZA; 5-azacytidine; 5-aza-CdR; 2â²-deoxy-5-azacytidine; 5-aza-CR; 5-azacytidine; AZN; Azanucleosides; BED; Biologically effective dose; BSC; Best supportive care;
The Ca2+/CaMKK2 axis mediates the telbivudine induced upregulation of creatine kinase: Implications for mechanism of antiviral nucleoside analogs' side effect
Keywords: آنالوگهای هسته ای; LdT; Telbivudine; HBV; hepatitis B virus; CHB; chronic Hepatitis B; CK; creatine kinase; HSKMCs; human skeletal muscle cells; SOD; superoxide dismutase; MDA; malondialdehyde; LPO; lipid peroxide; ROS; reactive oxygen species; CaMKK2; calmodulin-dependent
Baicalin benefits the anti-HBV therapy via inhibiting HBV viral RNAs
Keywords: آنالوگهای هسته ای; Baicalin; Anti-HBV; Nucleoside analog; HBV RNAs; Hepatocyte nuclear factors; BA; baicalin; HBV; hepatitis B virus; NAs; nucleoside analogs; ETV; entecavir; HNF; hepatocyte nuclear factor; qPCR; quantitative real-time PCR; pgRNA; pre-genomic RNA; DHBV; duc
Design, synthesis, and in vitro biological evaluation of novel 6-methyl-7-substituted-7-deaza purine nucleoside analogs as anti-influenza A agents
Keywords: آنالوگهای هسته ای; H1N1; H3N2; Influenza A; Nucleoside analogs;
UPLC–MS/MS method for the simultaneous quantification of anti-HBV nucleos(t)ides analogs: Entecavir, lamivudine, telbivudine and tenofovir in plasma of HBV infected patients
Keywords: آنالوگهای هسته ای; UPLC–MS/MS; Plasma; HBV; Nucleoside analogs; Entecavir
Chemoimmunotherapy for hairy cell leukemia
Keywords: آنالوگهای هسته ای; Hairy cell leukemia; Nucleoside analogs; Rituximab; Chemoimmunotherapy;
Studies on the preferred uracil-adenine base pair at the cleavage site of 10-23 DNAzyme by functional group modifications on adenine
Keywords: آنالوگهای هسته ای; 10-23 DNAzyme; Preferred cleavage site; Chemical modification; Functional nucleic acid; Nucleoside analogs;
HIV-1 and HSV-1 virus activities of some new polycyclic nucleoside pyrene candidates
Keywords: آنالوگهای هسته ای; Polycyclic aromatic hydrocarbons; Nucleoside analogs; Antiviral activities;
1,2,3-Triazoles as leaving groups in purine chemistry: a three-step synthesis of N6-substituted-2-triazolyl-adenine nucleosides and photophysical properties thereof
Keywords: آنالوگهای هسته ای; Triazolyl purine derivatives; Nucleophilic aromatic substitution; Click chemistry; Fluorescence; Nucleoside analogs;
Synthesis of novel NH-1,2,3-triazolo-nucleosides by the Banert cascade reaction
Keywords: آنالوگهای هسته ای; Nucleoside analogs; Fleximers; NH-1,2,3-Triazoles; Propargyl azides; Banert cascade reaction;
The effect of the acid-sensitivity of 4-(N)-stearoyl gemcitabine-loaded micelles on drug resistance caused by RRM1 overexpression
Keywords: آنالوگهای هسته ای; Hydrazone; Nucleoside analogs; Cell uptake; Intracellular metabolism; Lysosomes; dFdCTP/dNTP ratio;
Plug-and-play modules for flexible radiosynthesis
Keywords: آنالوگهای هسته ای; Automated radiosynthesis; High-pressure reactions; PET; D-[18F]FAC; Nucleoside analogs; Plug-and-play reconfiguration;
The role of nucleoside reverse transcriptase inhibitors usage in the incidence of hyperlactatemia and lactic acidosis in HIV/AIDS patients
Keywords: آنالوگهای هسته ای; Nucleoside analogs; Didanosine; Stavudine; Hyperlactatemia; Lactic acidosis
Investigations into specificity of azepinomycin for inhibition of guanase: Discrimination between the natural heterocyclic inhibitor and its synthetic nucleoside analogues
Keywords: آنالوگهای هسته ای; UCGMZXXEZQJTSR-OTBJXFPDSA-N; Synthesis; Azepinomycin; Nucleoside analogs; Biochemical studies; Inhibition of guanase (Guanine deaminase); Chiral chromatography;
Mutagen-mediated enhancement of HIV-1 replication in persistently infected cells
Keywords: آنالوگهای هسته ای; HIV-1; Lethal mutagenesis; Viral replication; HIV-1 persistent cell line; Nucleoside analogs; 5-hydroxy-2′-deoxycytidine (5-OHdC); 5-fluorouracil (5-FU); 2′,2′-difluoro-2′-deoxycytidine (gemcitabine)
Synthesis and antiviral activity of certain second generation methylenecyclopropane nucleosides
Keywords: آنالوگهای هسته ای; Antiviral agents; Nucleoside analogs;
Loading 3-deazaneplanocin A into pegylated unilamellar liposomes by forming transient phenylboronic acid-drug complex and its pharmacokinetic features in Sprague-Dawley rats
Keywords: آنالوگهای هسته ای; ANOVA; one-way analysis of variance; AUC0-â; area under the concentration-time curve from time zero to infinity; BW; body weight; cis diol; vicinal hydroxyl groups; CL; clearance; Cmax; maximum plasma concentration; Cr; creatinine; DZNep; 3-deazanep
Phosphorylation of deoxycytidine kinase on Ser-74: Impact on kinetic properties and nucleoside analog activation in cancer cells
Keywords: آنالوگهای هسته ای; CLL; dCTP; Deoxycytidine kinase; Nucleoside analogs; Ser-74 phosphorylation;
Nucleoside analogs induce proteasomal down-regulation of p21 in chronic lymphocytic leukemia cell lines
Keywords: آنالوگهای هسته ای; p53; p21 depletion; Nucleoside analogs; PCNA monoubiquitination; Cdk2; CLL
Synthesis and antiviral evaluation of α-l-2′-deoxythreofuranosyl nucleosides
Keywords: آنالوگهای هسته ای; Nucleoside analogs; Antivirals; Enzyme inhibitors; Prodrugs
Targeted endoradiotherapy using nucleotides
Keywords: آنالوگهای هسته ای; Endoradiotherapy; α Emitter; Auger emitter; Nucleoside analogs
The synthesis of piperidine nucleoside analogs-a comparison of several methods to access the introduction of nucleobases
Keywords: آنالوگهای هسته ای; Piperidine derivatives; Nucleoside analogs; Nucleobase; Proline; FFFXVCGDOSDSQW-UHFFFAOYSA-N; BBLDMGQRHJEJKW-UHFFFAOYSA-N; MWFGHPNPBJONPR-UHFFFAOYSA-N; VPHDNTATTQUPAM-UHFFFAOYSA-N; IXDWETHWMNXWIN-JGVFFNPUSA-N; RSMVNHYBPMZDRU-ZETCQYMHSA-N; QHMPGAJYIOCWJC-Q
Rapid synthesis of 2′,3′-dideoxy-3′β-fluoro-pyrimidine nucleosides from 2′-deoxypyrimidine nucleosides
Keywords: آنالوگهای هسته ای; Nucleoside analogs; Antiviral agents; Fluorination reaction; Diethylaminosulfur trifluoride
Fludarabine, cyclophosphamide, mitoxantrone plus rituximab (FCM-R) in frontline CLL <70 Years
Keywords: آنالوگهای هسته ای; Chronic lymphocytic leukemia (CLL); Chemoimmunotherapy; Mitoxantroe; Nucleoside analogs
A transient kinetic approach to investigate nucleoside inhibitors of mitochondrial DNA polymerase γ
Keywords: آنالوگهای هسته ای; Mitochondrial DNA polymerase gamma; Transient kinetics; Rapid chemical quench; HIV reverse transcriptase; NRTI; Nucleoside analogs; AIDS drugs;
Liquid chromatographic methods for the determination of endogenous nucleotides and nucleotide analogs used in cancer therapy: A review
Keywords: آنالوگهای هسته ای; Ribonucleotides; Deoxyribonucleotides; Mass spectrometry; Nucleoside analogs; Cancer therapy
Drosophila melanogaster deoxyribonucleoside kinase activates gemcitabine
Keywords: آنالوگهای هسته ای; Nucleoside analogs; Deoxyribonucleoside kinase; Gene-therapy; Cancer; Salvage pathway; Structure-function relationship;
Synthesis and antiviral activity evaluation of acyclic 2′-azanucleosides bearing a phosphonomethoxy function in the side chain
Keywords: آنالوگهای هسته ای; Azanucleosides; Acyclic nucleoside phosphonates; Nucleoside analogs; Antiviral agents; Sulfonamides
A sensitive LC–MS/MS method for quantification of a nucleoside analog in plasma: Application to in vivo rat pharmacokinetic studies
Keywords: آنالوگهای هسته ای; Nucleoside analogs; LC–MS/MS; Polar compounds; TFA; Validation and pharmacokinetic
Simultaneous quantification of 9-(β-d-1,3-dioxolan-4-yl)guanine, Amdoxovir and Zidovudine in human plasma by liquid chromatography–tandem mass spectrometric assay
Keywords: آنالوگهای هسته ای; Nucleoside analogs; Pharmacokinetics
Recent Progress in the Treatment of Acute Lymphoblastic Leukemia: Clofarabine
Keywords: آنالوگهای هسته ای; Acute lymphoblastic leukemia therapy; Novel agents; Nucleoside analogs; Relapsed acute lymphoblastic leukemia; High-risk acute lymphoblastic leukemia;
Synthesis of p-amino-WNA derivatives to enhance the stability of the anti-parallel triplex
Keywords: آنالوگهای هسته ای; Nucleoside analogs; Non-natural type triplex DNA; Rearrangement; Antigene;
Modulation of the human equilibrative nucleoside transporter1 (hENT1) activity by IL-4 and PMA in B cells from chronic lymphocytic leukemia
Keywords: آنالوگهای هسته ای; hENT1; IL-4; Chronic lymphocytic leukaemia; PKC; Fludarabine; Nucleoside analogs;
Polyadenylation inhibition by the triphosphates of deoxyadenosine analogues
Keywords: آنالوگهای هسته ای; RNA processing; Transcription; Polyadenylation inhibition; Nucleoside analogs; Cladribine; Clofarabine; Fludarabine
Synthesis and antiviral evaluation of acyclic azanucleosides developed from sulfanilamide as a lead structure
Keywords: آنالوگهای هسته ای; Azanucleosides; Nucleoside analogs; Antiviral agents; Sulfonamides
Cytostatic evaluations of nucleoside analogs related to unnatural base pairs for a genetic expansion system
Keywords: آنالوگهای هسته ای; Unnatural base pairs; Base analogs; Cytostatic activity; Nucleoside analogs; Antitumor drug
Tratamiento antirretroviral y toxicidad mitocondrial
Keywords: آنالوگهای هسته ای; Toxicidad mitocondrial; Mitocondria; Tratamiento antirretroviral; Análogos de los nucleósidos; Acidosis láctica; MiopatÃa; Mitochondrial toxicity; Mitochondrion; Antiretroviral therapy; Nucleoside analogs; Lactic acidosis; Miopathy;