Synergetic effect of Andrographis paniculata polysaccharide on diabetic nephropathy with andrographolide

► Andrographis paniculata is a traditional Chinese medicine. ► A water-soluble polysaccharide named as APP was isolated from A. paniculata. ► Diabetic nephropathy (DN) has already become the leading cause of end-stage renal disease. ► APP treatment could synergistically prevent the progression of DN complications.