In vitro antioxidant activities of the polysaccharides from Tricholoma lobayense

► The antioxidant activities of three polysaccharide components (TLH-1, TLH-2, TLH-3) extracted from Tricholoma lobayense. ► The polysaccharides had significant effect on scavenging O2−, inhibiting H2O2-induced MEH and formation of MDA. ► The effect of the polysaccharides on oxidation of HSA was evaluated by fluorescence spectroscopy. ► The polysaccharide TLH-3 had the highest capacity for scavenging free radicals and inhibiting oxidation of HSA. ► TLH-3 could be explored as effective natural antioxidant.