Steroid receptor coactivator-1: A versatile regulator and promising therapeutic target for breast cancer

► Breast cancer is deeply affected by steroids and their nuclear receptors. ► SRC-1 plays a pivotal role in mediating the activities of steroid nuclear receptors. ► SRC-1 is involved in the pathology and endocrine resistance of breast cancer. ► SRC-1 signalling pathway may be the potential therapeutic target for breast cancer.