Strychnine inhibits inflammatory angiogenesis in mice via down regulation of VEGF, TNF-α and TGF-β

► Strychnine inhibits sponge vascularization in sponge implant angiogenesis model. ► It downregulates VEGF, TNF-α, and TGF-β levels. ► Strychnine inhibits neutrophil accumulation and collagen deposition.