کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8344194 1541564 2011 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Moving toward personalized cell-based interventions for adrenal cortical disorders: Part 2 - Human diseases and tissue engineering
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Moving toward personalized cell-based interventions for adrenal cortical disorders: Part 2 - Human diseases and tissue engineering
چکیده انگلیسی
Transdifferentiation of an individual's own cells into functional differentiated cells to replace an organ's lost function would be a personalized approach to therapeutics. In this two part series, we will describe the progress toward establishing functional transdifferentiated adrenal cortical cells. In this article (Part 2), we describe the disorders of the adrenal cortex, therefore establishing why there is the need for personalized cell-based therapy for individuals with these disorders. We then present our pilot studies of cell transdifferentiation toward an adrenal cortical fate using genes described in the first article of this pair (Part 1).
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Molecular Genetics and Metabolism - Volume 104, Issues 1–2, September–October 2011, Pages 80-88
نویسندگان
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