cGMP modulates Arabidopsis lateral root formation through regulation of polar auxin transport

► cGMP as signaling molecule is involved in regulating polar auxin transport in Arabidopsis root. ► cGMP regulates the auxin influx and efflux carriers gene expression (PIN1, PIN2, PIN3, PIN7, AUX1, PGP1 and PGP19). ► cGMP affects polar distribution of PIN protein mediated by actin cytoskeleton. ► Ly83583 affects actin organization and localization. ► cGMP significantly affects Arabidopsis lateral root development.