A novel chimeric MOMP antigen expressed in Escherichia coli, Arabidopsis thaliana, and Daucus carota as a potential Chlamydia trachomatis vaccine candidate

► We designed a Chlamydia trachomatis MOMP chimera containing major antigenic epitopes. ► The chimera was successfully produced in Escherichia coli, carrot, and Arabidopsis thaliana. ► Arabidopsis plants stably express the MOMP chimera over at least six generations. ► Purified MOMP chimera retained antigenicity when injected into rabbits. ► Anti-MOMP chimera antibodies were reactive against C. trachomatis elementary bodies.