Effect of exenatide on cholecystokinin-induced gallbladder emptying in fasting healthy subjects

► This study evaluated the effects of exenatide on fasting CCK-induced gallbladder emptying. ► Exenatide did not affect pre-CCK gallbladder volume or ejection fraction. ► With CCK, exenatide decreased ejection fraction but not gallbladder volume. ► Exenatide did not affect pancreatic or bile duct diameters. ► Exenatide reduced CCK-induced gallbladder emptying compared to placebo.