Relationship of fetuin-A levels to weight-dependent insulin resistance and type 2 diabetes mellitus

► Fetuin-A may play a role in insulin resistance. ► The relationship between fetuin-A and parameters of insulin resistance was examined. ► At the early stage of weight gain fetuin-A could be of relevance for insulin resistance. ► In the obese state and in type 2 Diabetes fetuin-A seems to be of minor importance.