Low pre-transplant adiponectin multimers are associated with adverse allograft outcomes in kidney transplant recipients a 3-year prospective study

► Endothelial dysfunction is a universal risk factor for kidney allograft failure. ► Adiponectin prevents endothelial damage in early stages of atherosclerosis. ► We investigated the role of adiponectin in endothelial dysfunction and long-term allograft outcome. ► Adiponectin independently predicted increased risk of allograft failure after 3 years.