Association of expression of XIAP-associated factor 1 (XAF1) with clinicopathologic factors, overall survival, microvessel density and cisplatin-resistance in ovarian cancer

► We analyzed XAF1 and XIAP expressions in ovarian tumors. ► Association of XAF1 and XIAP with prognostic factors and MVD was analyzed. ► XAF1 inhibited tumor growth and decreased MVD in vivo. ► XAF1 enhanced SKOV3 cells sensitivity to cisplatin and the mechanism was described.