Regulation of IGF-1 but not TGF-β1 by NGF in the smooth muscle of the inflamed urinary bladder

► Increases in NGF in the urothelium during cystitis. ► Increases in IGF-1 and TGF-β1 in the detrusor muscle during cystitis. ► NGF regulates IGF-1 but not TGF-β1 in the detrusor muscle.