Effect of dietary fatty acid composition on food intake, triglycerides, and hypothalamic peptides

► A meal higher in saturated vs. unsaturated fat stimulates circulating triglycerides. ► A meal higher in saturated vs. unsaturated fat stimulates subsequent food intake. ► A meal higher in saturated vs. unsaturated fat stimulates hypothalamic peptides. ► A diet higher in saturated vs. unsaturated fat has similar effects to acute meals. ► Lowering triglycerides has effects opposite those of a meal higher in saturated fat.