Optimal design for studying mucoadhesive polymers interaction with gastric mucin using a quartz crystal microbalance with dissipation (QCM-D): Comparison of two different mucin origins

Scheme of the experiment described in the protocol. Only one overtone is represented. Blue arrow indicates when the mucin solution enters the QCM-D module. Red arrow indicates when the polymer solution enters the module. Black arrow indicates the introduction of buffer solution. Gold bar, cyan line, and red circle with black coating indicate the crystal sensor, mucins and polymers, respectively.99