کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8500749 1553763 2014 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Lethal Herpesvirosis in 16 Captive Horned Vipers (Vipera ammodytes ammodytes): Pathological and Ultrastructural Findings
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
Lethal Herpesvirosis in 16 Captive Horned Vipers (Vipera ammodytes ammodytes): Pathological and Ultrastructural Findings
چکیده انگلیسی
Sixteen captive adult horned vipers (Vipera ammodytes ammodytes) were submitted for necropsy examination following a 2-week history of lethargy, anorexia and dyspnoea. Gross lesions included widespread haemorrhage, serosanguineous effusions in the body cavities and multiple pinpoint white to yellow foci in the liver. Microscopically, there was multifocal hepatic coagulative necrosis associated with intranuclear acidophilic inclusion bodies in sinusoidal endothelial cells. Similar endothelial lesions were observed in the myocardium, fat bodies, kidneys and spleen. Transmission electron microscopy revealed numerous virions (100-110 nm) in the nuclei of endothelial cells and intracytoplasmic enveloped virions (140-150 nm) were also found. The gross and histological findings and the ultrastructural features of the intranuclear inclusions and viral particles were consistent with herpesviral infection. To the best of our knowledge, these are the first reported cases of a lethal herpesvirosis in horned vipers and the second report in snakes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Comparative Pathology - Volume 150, Issues 2–3, February–April 2014, Pages 341-344
نویسندگان
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