کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8504117 | 1554326 | 2018 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Spermatogonia survival in young ram lambs following irradiation, Busulfan or thermal treatment
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم دامی و جانورشناسی
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چکیده انگلیسی
The impact of irradiation doses (0-15âGy) delivered with high precision to the testis by a 6âMV photon beam was assessed by serial biopsies. Sertoli cell numbers were depleted by 90% at 3 weeks in 15âGy treated testes. Spermatogonia were depleted 8 weeks after irradiation with 9âGy, 12âGy and 15âGy. By 13 weeks, only in the 15âGy treated testes were spermatogonia and Sertoli cell numbers lower. At 13 weeks testis atrophy resulted in 3/6 lambs irradiated with 12âGy or 15âGy. Irradiation of very young lambs clearly compromised testis function, thermal treatment was ineffective and busulfan treatment resulted in minimal effects.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Small Ruminant Research - Volume 166, September 2018, Pages 22-27
Journal: Small Ruminant Research - Volume 166, September 2018, Pages 22-27
نویسندگان
Jeanette Olejnik, Natalka Suchowerska, Muren Herrid, Michael Jackson, Geoff Hinch, Jonathan Hill,