Effect of Zembrin® and four of its alkaloid constituents on electric excitability of the rat hippocampus

Effects of 5 mg/kg of Zembrin® in the presence of glutamate receptor agonists (x-axis). Results from slices as obtained during theta burst stimulation. Data are given as mean ± S.E.M. Amplitude of the signal is given as voltage in mV (y-axis). Dark graphs represent the action of glutamate receptor agonists alone (reference data from an earlier experimental series), grey graphs show the population spike amplitudes measured in slices from animals pre-treated with 5 mg/kg Zembrin®. Statistical significance of p < 0.01 is marked by stars.108