کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8630204 | 1568779 | 2018 | 26 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Nanotechnology based approaches for anti-diabetic drugs delivery
ترجمه فارسی عنوان
روشهای مبتنی بر فناوری نانو برای تحویل داروهای ضد دیابت
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کلمات کلیدی
فناوری نانو، انسولین، دیابت، تحویل مواد مخدر،
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
علوم غدد
چکیده انگلیسی
Nanotechnology science has been diverged its application in several fields with the advantages to operate with nanometric range of objects. Emerging field of nanotechnology has been also being approached and applied in medical biology for improved efficacy and safety. Increased success in therapeutic field has focused several approaches in the treatment of the common metabolic disorder, diabetes. The development of nanocarriers for improved delivery of different oral hypoglycemic agents compared to conventional therapies includes nanoparticles (NPs), liposomes, dendrimer, niosomes and micelles, which produces great control over the increased blood glucose level and thus becoming an eye catching and most promising technology now-a-days. Besides, embellishment of nanocarriers with several ligands makes it more targeted delivery with the protection of entrapped hypoglycaemic agents against degradation, thereby optimizing prolonged blood glucose lowering effect. Thus, nanocarriers of hypoglycemic agents provide the aim towards improved diabetes management with minimized risk of acute and chronic complications. In this review, we provide an overview on distinctive features of each nano-based drug delivery system for diabetic treatment and current NPs applications in diabetes management.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diabetes Research and Clinical Practice - Volume 136, February 2018, Pages 52-77
Journal: Diabetes Research and Clinical Practice - Volume 136, February 2018, Pages 52-77
نویسندگان
Prashant Kesharwani, Bapi Gorain, Siew Yeng Low, Siew Ann Tan, Emily Chai Siaw Ling, Yin Khai Lim, Chuan Ming Chin, Pei Yee Lee, Chun Mey Lee, Chun Haw Ooi, Hira Choudhury, Manisha Pandey,