کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8633929 | 1569086 | 2018 | 37 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A high weekly dose of cholecalciferol and calcium supplement enhances weight loss and improves health biomarkers in obese women
ترجمه فارسی عنوان
دوز بالای کولاکسیفرول و مکمل کلسیم در هفته هفتگی باعث کاهش وزن و بهبود زیست شناسی سلامتی در زنان چاق می شود
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کلمات کلیدی
TEEFBGiPTHLSDCholecalciferolBMRTSHIRBpTH25(OH)D - 25 (OH) D25-hydroxyvitamin D - 25 هیدروکسی ویتامین Dleast significant difference - حداقل تفاوت قابل توجهیWaist circumference - دور کمرHealth - سلامتیbody mass index - شاخص توده بدنBMI - شاخص توده بدنیfasting blood glucose - قند خون ناشتاBlood metabolites - متابولیت های خونObesity - مرض چاقیbasal metabolic rate - میزان متابولیسم پایهwaist-to-hip ratio - نسبت دور کمر به رانThyroid-stimulating hormone - هورمون تحریک کننده تیروئیدparathyroid hormone - هورمون پاراتیروئیدIntact parathyroid hormone - هورمون پاراتیرویید بدون دردinstitutional review board - هیئت بررسی نظارتTotal Energy Expenditure - کل هزینه انرژیCalcium - کلسیم
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
علوم غدد
چکیده انگلیسی
Obesity, a chronic condition associated with several life-threatening diseases, affects a significant proportion of the global population and has long been associated with vitamin D deficiency. The prevalence of both obesity and vitamin D deficiency has increased dramatically in Jordan in recent decades, especially among women. Few studies in Jordan and the surrounding area address this issue. In this study, we hypothesize that calcium and vitamin D have beneficial effects on weight reduction and metabolic profile in obese women. The objective of this study is to examine the effect of vitamin D3 and calcium supplementation on anthropometric measurements and some blood metabolites. Forty-five obese female subjects with vitamin D deficiency were recruited by a dietitian and randomly assigned to the same weight loss diet in addition to the following treatments (4 groups): control (CON), no prescribed supplements; vitamin D3 (Diet/D), given a high weekly dose of cholecalciferol (50 000 IU/subject/week); calcium (Diet/Ca), given 1200 mg/dL calcium/subject/day; vitamin D3 plus Ca (Diet/Ca/D), given cholecalciferol (50 000 IU/subject/week) and calcium (1200 mg/dL calcium/subject/day). Results revealed that after 3 months of supplementation, the Diet/Ca/D group subjects experienced a significant reduction (P ⤠.05) in weight (10.49 kg), BMI (4.61 ± 2 kg/m2), waist circumference (11.41 ± 8.9 cm), body fat percentage (2.43 ± 1.7%), FBG (25.81 ± 11.4 mg/dL), PTH (27.58 ± 8.9 pg/mL), cholesterol (0.56 ± 0.2 mmol/L), and triglycerides (0.53 ± 0.21 mmol/L) when compared to the Diet/Ca and the CON groups. Interestingly, however, the CON group showed a significant increase in serum PTH concentration (9.51 ± 3.8 pg/mL, P ⤠.05). Based on these results, a combined Ca and vitamin D3 supplement appears to enhance weight loss and improve some of the blood metabolic profiles in obese women subjected to a weight loss diet, thus supporting our study hypothesis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nutrition Research - Volume 59, November 2018, Pages 53-64
Journal: Nutrition Research - Volume 59, November 2018, Pages 53-64
نویسندگان
Hadil S. Subih, Zainab Zueter, Bayan M. Obeidat, Mohammad A. al-Qudah, Sana'a Janakat, Fadwa Hammoh, Ghazi Sharkas, Hiba A. Bawadi,