کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8648252 | 1570441 | 2018 | 20 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Top surface blade residues and the central channel water molecules are conserved in every repeat of the integrin-like β-propeller structures
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شناسی مولکولی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Top surface blade residues and the central channel water molecules are conserved in every repeat of the integrin-like β-propeller structures Top surface blade residues and the central channel water molecules are conserved in every repeat of the integrin-like β-propeller structures](/preview/png/8648252.png)
چکیده انگلیسی
An integrin-like β-propeller domain contains seven repeats of a four-stranded antiparallel β-sheet motif (blades). Previously we described a 3D structural motif within each blade of the integrin-type β-propeller. Here, we show unique structural links that join different blades of the β-propeller structure, which together with the structural motif for a single blade are repeated in a β-propeller to provide the functional top face of the barrel, found to be involved in protein-protein interactions and substrate recognition. We compare functional top face diagrams of the integrin-type β-propeller domain and two non-integrin type β-propeller domains of virginiamycin B lyase and WD Repeat-Containing Protein 5.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Structural Biology - Volume 201, Issue 2, February 2018, Pages 155-161
Journal: Journal of Structural Biology - Volume 201, Issue 2, February 2018, Pages 155-161
نویسندگان
Alexander Denesyuk, Konstantin Denessiouk, Mark S. Johnson,