Keywords: Cytokine; G-CSF; Backbone circularization; X-ray crystallography; Protein engineering; G-CSF; Granulocyte colony-stimulating factor; PDB; Protein Data Bank; RMSD; Root mean squared deviation;
مقالات ISI (ترجمه نشده)
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Keywords: CA; carbonic anhydrase; SspCA; carbonic anhydrase from Sulfurihydrogenibium yellowstonense YO3AOP1; TaCA; carbonic anhydrase from Thermovibrio ammonificans; SazCA; carbonic anhydrase from Sulfurihydrogenibium azorense; PMCA; carbonic anhydrase from Persep
Keywords: AOI; animal-origin ingredients; IRMS; isotope ratio mass spectrometer; PDB; PeeDee Belemnite; Carbon isotope; Half-life; Metabolism; Poultry; Turnover;
Keywords: Monocaprin; Food spoilage fungi; Food preservative; Mechanism of action; DIZ; Diameter of inhibition zone; MFC; Minimum fungicidal concentration; MIC; Minimum inhibitory concentration; PBS; Phosphate buffer saline; PDA; Potato dextrose agar; PDB; Potato d
Keywords: Beta cells; Islets; Monoclonal antibody; Recombinant antibody, antigen-binding fragment; Humanisation; APC; allophycocyanin; CDR; complemetarity determining region; Cy3/Cy7; cyanin 3/cyanin 7; Fab; antigen-binding fragment of immunoglobulin; Fc; constant
Keywords: ASD; Asparagine Synthetase Deficiency; ASNase; Asparaginase; ASNS; asparagine synthetase; CARE; C/EBP-ATF response element; CSF; cerebral spinal fluid; EEG; electroencephalogram; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; PDB; protein data base; SD;
Keywords: QM/MM; quantum mechanics/molecular mechanics; XB; halogen bonding; X; halogen; D; donor group; A; acceptor group; ESP; electrostatic potential; HB; hydrogen bonding; PDB; protein data bank; DFT; density functional theory; RESP; restrained electrostatic po
Keywords: AA; acrylamide; FAO/WHO; food and agriculture organization of the united nations and world health; HS-SPME-GC-FID; headspace solid-phase microextraction-gas chromatography-flame ionization detection; LC-MS/MS; liquid chromatography-tandem mass spectrometr
Keywords: GH; glycoside hydrolase; CtCel5E; Clostridium thermocellum Cel5E; TmCel5A; Thermotoga maritima Cel5A; RtCelB; Ruminiclostridium thermocellus CelB; CMC; carboxymethyl cellulose; BWX; beechwood; TLC; thin-layer chromatography; PDB; protein data bank; LB; Lu
Keywords: CRD; Cysteine-rich domain; GPCR; G protein coupled receptors; GTs; Glycosylated terpenoids; mGluR3; Metabotropic glutamate receptor 3; MPA; MultiPoint Attachment model; PDB; Protein data bank; QSAR; Quantitative Structure-Analysis Relationship; SG; Stevio
Keywords: AIns; iatrogenic insulin amyloid; ThT; thioflavin T; ANS; 8 anilinonaphthalene-1-sulfonic acid; APRs; aggregation prone regions; hIAPP; human islet amyloid polypeptide; CD; circular dichroism; TEM; transmission electron microscopy; PDB; protein data bank;
Keywords: APP; amyloid precursor protein; CASP6; caspase-6; Co-IP; co-immunoprecipitation; CRM; cis-regulatory module; DDBJ; DNA Data Bank of Japan; EMBL; European Molecular Biology Laboratory; HD; Huntington disease; HTT; huntingtin; IPI; International Protein Ind
Keywords: ASS; atypical apraxia of speech; ALS; amyotrophic lateral sclerosis; ATG; autophagy-related; BD; Behçet disease; BPAN; Ã-propeller protein associated neurodegeneration; CMT2B; Charcot-Marie-Tooth neuropathy 2B; DMRV; distal myopathies with rimmed vacuol
Keywords: Transglycosylase; Moenomycin; Inhibitor; Biphenyl; Phosphorylpropanoate; Amine linker; A. baumannii; Acinetobacter baumannii; Arg; arginine; Asn; asparagine; Asp; aspartic acid; ATCC; american type culture collection; DMF; N,N-dimethylformamide; DMSO; di
Keywords: CGA; chlorogenic acid; ELISA; Enzyme-Linked Immuno Sorbent Assay; OD; optical density; PDA; potato dextrose agar; PDB; potato dextrose broth; Antifungal; Biofungicide; Biopesticide; Industrial by-product; Phenolic compounds; Phytopathogenic fungi;
Keywords: SCD; Sickle Cell Disease; NEAT; NEAr heme Transporter; MD; Molecular Dynamics; Hb; Hemoglobin; Isd; Iron-regulated surface determinant proteins; AMBER; Assisted Model Building with Energy Refinement; PDB; Protein Data Bank; COM; Center Of Mass; HP; Haptog
Keywords: RNases; Insecticidal; Sarcin; Hirsutellin; Anisoplin; CD; circular dichroism; HtA; Hirsutellin A; PDB; Protein Data Bank; SEM; standard error of the mean; SRL; sarcin-ricin loop; WT; wild-type; Tm; melting temperature;
Keywords: GPSC; Gaoping submarine canyon; IRMS; isotope ratio mass spectrometer; OCf; fossil organic carbon; OCnf; biospheric non-fossil carbon; PDB; Pee Dee Belemnite; POC; particulate organic carbon; POM; particulate organic matter; TN; total nitrogen; TOC; total
Keywords: IPDM; intramolecular peptide disulfide motif; ATAP; animal toxin annotation project; PDB; Protein Data Bank; RASA; relative accessible surface area; ICK motif; Inhibitory Cystine Knot motif; Intramolecular peptide disulfides; Diversity of cysteine pattern
Keywords: RPD; repeat protein domain; MSA; multiple sequence alignment; PPI; protein-protein interaction; TPR; tetratricopeptide repeat; ANK; Ankyrin repeat; ExAC; Exome Aggregation Consortium; SNV; single nucleotide variant; DAF; derived allele frequency; PDB; P
Proteome-wide identification of lysine succinylation in thermophilic and mesophilic bacteria
Keywords: COGs; Clusters of orthologous groups; KAT; lysine acyltransferase; KDAC; lysine deacylase; LC-MS/MS; liquid chromatography-tandem mass spectrometry; PBS; phosphate buffered saline; PDB; Protein Data Bank; PTM; post-translational modification; RCSB; Resear
Keywords: APR; aggregation-prone region; FR; framework region; CDR; complementarity-determining region; RALS; right angle light scattering; FDA; US Food and Drug Administration; PDB; Protein Data Bank; MASS; mutant aggregation and stability spectrum; SEC; size-excl
Keywords: Dual EGFR/HER2 inhibitors; Resistance; T790M/L858R mutant EGFR; Irreversible inhibitors; ADMET; Absorption/Distribution/Metabolism/Excretion/Toxicity; Cbl; Casitas B-lineage Lymphoma; c-MET; cellular mesenchymal to epithelial transition factor; DM; double
Keywords: SDF; Structure data file; PDB; Protein data bank; Cellulase; Aspergillus; Trichoderma; Homology modeling; Molecular docking;
Keywords: BCAA; branched-chain amino acids; EAA; essential amino acids; BCAT; branched-chain aminotransferase; BCKDH; branched-chain α-keto acid dehydrogenase; PDB; protein data bank; RMSD; root mean square deviation; Branched-chain amino acids (BCAA); Homology mo
The role of metal substitution in the promiscuity of natural and artificial carbonic anhydrases
Keywords: B3LYP; Becke 3 parameter Lee - Yang - Parr functional; CA; carbonic anhydrase; CHARMM; Chemistry at HARvard Molecular Mechanics; DFT; density functional theory; FF; force field; MD; Molecular Dynamics; NAMD; Nanoscale Molecular Dynamics; NBO; Natural
Keywords: BBB; blood-brain barrier; CNS; central nervous system; HAT; human African trypanosomiasis; NTDs; neglected tropical diseases; PDB; Protein Data Bank; PPPs; public-private partnerships; R&D; research and development; RNAi; RNA interference; SBDD; structure
Keywords: Alzheimer's disease; Ferulic acid-O-alkylamines derivatives; Multifunctional agents; Butyrylcholinesterase inhibition; Aβ aggregation; Antioxidant activity; Neuroprotective effects; BuChE; butyrylcholinesterase; AChE; acetylcholinesterase; Aβ; β-amyloi
Keywords: AP; action potential; CaMKII; Ca2+/calmodulin-dependent protein kinase II; CaT; Ca2+ transient; dF/dtmax; rate of contraction force rise; dF/dtmin; rate of contraction force fall; dP/dtmax; LV pressure rise; dP/dtmin; LV pressure fall; DPP-4; dipeptidyl p
Recent advancements in the development of anti-tuberculosis drugs
Keywords: ADRs; adverse drug reactions; AG; arabinogalactan; AhpE; alkylhydroperoxide reductase E; Alr; d-alanine racemase; AMP; adenosine monophosphate; AnPRT; anthranilate phosphoribosyltransferase; ATP; adenosine triphosphate; BTZ; benzothiazinone; CADD; compute
Keywords: AIDS; acquired immune deficiency syndrome; ALV; avian leukosis virus; AMV; avian myeloblastosis virus; APOBEC; apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like; ASLV; avian sarcoma leukosis virus; AZT; 3â² -azido-3â² -deoxythymidine; BIV;
Keywords: 3-BC; 3-benzylidene camphor; 4-MBC; 4-methylbenzylidene camphor; Aβ; amyloid-β; ABAD; Aβ-binding alcohol dehydrogenase; AD; Alzheimer's disease; AI; aromatase inhibitor; AKR; aldo-keto reductase; AME; apparent mineralocorticoid excess; AR; androgen r
Keywords: ANCOVA; analysis of covariance; CVAFS; cold vapor atomic fluorescence spectrometry; d. wt.; dry weight; df; degrees of freedom; DIW; deionized water; DOC; dissolved organic carbon; FWMF; food web magnification factor; Hg; mercury; Hginorg; inorganic mercu
Keywords: AA; arachidonic acid; AKR; aldo-keto reductase; AOS; allene oxide synthase; CX; carbon numbers; COX; cyclooxygenase; cPGES; cytosolic PGE synthase; cPLA2; cytosolic phospholipase A2; CYP; cytochrome P450; DGLA; dihomo-γ-linolenic acid; DP; prostaglandin
Rational design of metalloenzymes: From single to multiple active sites
Keywords: UAAs; unnatural amino acids; Rd; rubredoxin; EPR; electron paramagnetic resonance; Az; azurin; SOR; superoxide reductase; PDB; protein data bank; 6-PGLac; 6-phosphogluconolactonase; H-bond; hydrogen-bond; NIR; nitrite reductase; ET; electron transfer; 3SC
Keywords: Ginkgo biloba; Chymase; Herbal nutraceutical; Screening; Molecular docking; Inhibitor; Cardiovascular diseases; GB; Ginkgo biloba; OHH; 2-[3-{methyl [1-(2-naphthoyl) piperidin-4-yl] amino} carbonyl)-2-naphthyl]-1-(1-naphthyl)-2-oxoethylphosphonic acid; PD
Keywords: Aβ; amyloid β-peptides; Caco-2; caucasian colon adenocarcinoma-2; FBS; foetal bovine serum; Hec-1a; human endometrial cancer - 1a; INS; insulin; KPI; kidney bean protein isolate; OVA; ovalbumin; PBS; phosphate buffered saline; PDB; protein data bank;
Keywords: Tyrocidines; Antimicrobial peptides; Antifungal activity; Mode of action; Model membrane permeabilisation; Filamentous fungi; A. fumigates; Aspergillus fumigates; A. niger; Aspergillus niger; ATCC; American Type Culture Collection; Bot. cinerea; Botryti
Keywords: high molecular weight products; fibrillation; covalent insulin dimer; SAXS; X-ray crystallography; ThT assay; DLS; dynamic light scattering; HMWP; high molecular weight products; nOe; nuclear overhauser effect; NOESY; nuclear overhauser effect spectroscop
Keywords: Small angle X-ray scattering; Complex structural analysis; Intrinsically disordered proteins; Advanced sample environments; Hybrid biostructural analysis; SAS; small angle (X-ray/neutron) solution scattering; SAXS; small angle X-ray scattering; SANS; smal
Keywords: PFC; protein family cluster; KO; KEGG orthology pathway; NemFam; PFC with at least 1 nematode species; RefFam; PFC with at least 1 non-nematode species; PDB; RCSB Protein Data Bank; Insertions and deletions; Adaptation; Spatial structures of proteins; Dru
Keywords: AMA; amantadine; BFM; bond fluctuation method; BST-2; bone marrow stromal cell antigen 2; CD; circular dichroism; CGMD; coarse-grained molecular dynamics; ClyA; cytolysin A; DHPC; dihexanoylphosphocholine; DPC; dodecylphosphocholine; E. coli; Escherichia
Keywords: REU; Rosetta energy units; PDB; Protein Data Bank; SEC; size-exclusion chromatography; GuHCl; guanidine hydrochloride; DSS; 4,4-dimethyl-4-silapentane-1-sulfonic acid; pl; isoelectric point; computational protein design; de novo protein design; Rosetta; p
Keywords: Protein stability; Stabilization centers; Stability changing mutations; Thermal stability; Thermophiles; CD; Circular Dichroism; DSC; Differential Scanning Calorimetry; PDB; Protein Data Bank; SC; Stabilization Center; SCE; Stabilization Center Element;
Keywords: A; Acetone extract; AAE; Water-acetone extract; AC; Alliun cepa; ACE; Acetate extract; AE; Aqueous extract; AEE; Hydroalcoholic extract; AI; Apoptosis-inducing; Ames; Bacterial reverse mutation assay; AN; Aspergillus nidulans; ANVISA; Agência Nacional
Keywords: AKH; adipokinetic hormone; CHO; Chinese hamster ovary; Crypα; cell adhesion molecule-like tyrosine phosphatase α; Endo H; Endoglycosidase H; ENG; endoglin/CD105; HEK; human embryonic kidney; IMAC; immobilized metal affinity chromatography; MBP; maltose-
Keywords: TF; Transcription factor; DNA; Deoxyribonucleic acid; PDB; Protein Data Bank; RMSD; Root mean squared deviation; Pathogenic organisms; Transcription factors; Mutations; Different roles; Disease propagation;
Keywords: Aβ; β-Amyloid peptide; Aβ40; 40-amino acid isoform of β-Amyloid peptide; Aβ42; 42-amino acid isoform of β-Amyloid peptide; Aβ42/Aβ40; ratio of measured steady-state levels of Aβ42 and Aβ40; AD; Alzheimer's Disease; AICD; APP intracellular domain
Keywords: Bisbenzimidazole derivatives; Specific inhibitors of the trypsin-like sites; Constitutive proteasome; Immunoproteasome; In silico docking; c20S; 20S constitutive proteasome catalytic core; cChT-L (β5c subunit); chymotrypsin-like; cT-L (β2c subunit); try
Keywords: EFTF; eye field transcription factors; Md; the ratio of residue substitution in DNA-binding domains; Mn; the ratio of residue substitution in non-DNA-binding domains; PDB; Protein Data Bank; Ancestral structure estimation; Evolution of eye development; Tr