دانلود مقالات ISI درباره Pdb + ترجمه فارسی

Picornaviral polymerase structure, function, and fidelity modulation

Keywords: 3Dpol; picornavirus RNA-dependent RNA polymerase; CTP; cytosine triphosphate; CV; coxsackievirus B3; EC; polymerase-RNA elongation complex; EMCV; encephalomyocarditis virus; EV71; enterovirus 71; FMDV; foot-and-mouth disease virus; HCV; hepatitis C virus;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

Targeting Wnt-driven cancers: Discovery of novel tankyrase inhibitors

Keywords: Tankyrase inhibitors; PARP family; Wnt/β-catenin signaling pathway; Wnt pathway disruption; Wnt-driven cancers; APC; adenomatous polyposis coli gene product; ARTD; ADP-ribosyltransferases; CK1; casein kinase 1; DMPK; drug metabolism and pharmacokinetics;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

Free Energy Perturbation Calculation of Relative Binding Free Energy between Broadly Neutralizing Antibodies and the gp120 Glycoprotein of HIV-1

Keywords: bNAbs; broadly neutralizing antibodies; CDR H2; second heavy chain complementarity-determining region; FEP; free energy perturbation; MD; molecular dynamics; GPU; graphics processing unit; RMSE; RMS error; RSC3; resurfaced stabilized core 3; PDB; protein

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه

Rubredoxins derivatives: Simple sulphur-rich coordination metal sites and its relevance for biology and chemistry

Keywords: Rd; rubredoxin; Dx; Desulforedoxin; Cp.; Clostridium pasturium; Dg.; Desulfovibrio gigas; Dd.; Desulfovibrio desulfuricans; Dv.; Desulfovibrio vulgaris; Pf.; Pyrococcus furiosus; X; amino acid residue; WT; wild type; ZFs; Zinc fingers; MT; metallothionein

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Unique binding mode of Evogliptin with human dipeptidyl peptidase IV

Keywords: Dipeptidyl peptidase IV; DPP4; Evogliptin; Diabetes; Inhibitor; Complex structure; DPP4; dipeptidyl peptidase-IV; GLP-1; glucagon-like peptide-1; PDB; protein data bank; RMSD; root-mean-square deviation;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Engineered polyketides: Synergy between protein and host level engineering

Keywords: Polyketide; Polyketide synthase; Natural products; Commodity chemical; Metabolic engineering; Synthetic biology; PK; Polyketide; PKS; Polyketide synthase; FAS; Fatty acid synthases; KS; Ketosynthase; AT; Acyltransferase; ACP; Acyl carrier protein; DH; Deh

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

Target Residence Time-Guided Optimization on TTK Kinase Results in Inhibitors with Potent Anti-Proliferative Activity

Keywords: TTK; threonine tyrosine kinase; SAC; spindle assembly checkpoint; TNBC; triple-negative breast cancer; SPR; surface plasmon resonance; PDB; Protein Data Bank; PEG; polyethylene glycol; DMSO; dimethylsulfoxide; ATCC; American Type Culture Collection; targe

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

Molecular dynamics simulations of Zika virus NS3 helicase: Insights into RNA binding site activity

Keywords: Zika virus; Flavivirus; NS3 helicase; Molecular dynamics; FTMap; Drug discovery; ZIKV; Zika virus; NS; non-structural; NS3h; NS3 helicase; PrM; membrane precursor; MD; molecular dynamics; RMSF; root mean square fluctuation; PDB; protein data bank; VMD; Vi

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Na+/K+-ATPase interaction with methylglyoxal as reactive metabolic side product

Keywords: aa residue; amino acid residue; AMG; aminoguanidine, also pimagedine; Arg (R); arginine; ATP; adenosine triphosphate; BSA; bovine serum albumin; CHER; catalytic hydrogen evolution reaction; CML; Nε-(carboxymethyl)lysine; CPS; constant-current chronopoten

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Role of per-oral pancreatoscopy in the evaluation of suspected pancreatic duct neoplasia: a 13-year U.S. single-center experience

Keywords: BD; branch duct; FN; false negative; FP; false positive; IPMN; intraductal papillary mucinous neoplasm; MD; main duct; NPV; negative predictive value; PAB; POP-assisted biopsy; PD; pancreatic duct; PDB; POP-directed biopsy; POP; per-oral pancreatoscopy; P

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Lawsone derivatives target the Wnt/β-catenin signaling pathway in multidrug-resistant acute lymphoblastic leukemia cells

Keywords: ABC; ATP-binding cassette; ALL; acute lymphoblastic leukemia; CRD; cysteine-rich domain; DMSO; dimethyl sulfoxide; FZD; Frizzled receptor; IC50,; 50% inhibition concentration; LPR5; lipoprotein-related protein 5; MDR; multidrug resistance; PDB; protein da

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Structure-function studies of BPP-BrachyNH2 and synthetic analogues thereof with Angiotensin I-Converting Enzyme

Keywords: Docking; Molecular dynamics simulations; Molecular mechanics Poisson-Boltzmann surface area; g_mmpbsa; proline-Rich oligopeptide; Toxicological prediction; ACE; Angiotensin-I converting enzyme; ADT; AutoDock Tools; CC50; Mean cytotoxic concentration; IC50

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

In silico identification of novel antagonists and binding insights by structural and functional analyses of guanylate kinase of Leishmania donovani and interaction with inhibitors

Keywords: GK; guanylate kinase; VL; visceral leishmaniasis; GMPK; guanosine monophosphate kinase; 5GP; 5′-guanylic acid; GOLD; genetic optimization for ligand docking; CHARMM; chemistry of HARvard molecular mechanics; BLAST; basic local alignment search tool; PDB

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Exploring putative inhibitors of Death Associated Protein Kinase 1 (DAPK1) via targeting Gly-Glu-Leu (GEL) and Pro-Glu-Asn (PEN) substrate recognition motifs

Keywords: DAPK1; Death Associated Protein Kinase 1; NMDARs; N-methyl-D-aspartate receptors; NMDAR2A or NR2A; N-methyl-D-aspartate receptor subtype 2A; NMDAR2B or NR2B; N-methyl-D-aspartate receptor subtype 2B; NSC; neuronal survival-signaling complex; NDC; neuronal

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Iminoenamine based novel androgen receptor antagonist exhibited anti-prostate cancer activity in androgen independent prostate cancer cells through inhibition of AKT pathway

Keywords: Prostate cancer; T877A; Androgen receptor antagonist; Bicalutamide; LNCaP; Apoptosis; AR; Androgen receptor; DHT; Dihydrotestosterone; AIPC; Androgen Independent Prostate Cancer; LBD; Ligand Binding Domain; R-BIC; R-Bicalutamide; ETS; Erythroblast Transfo

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

Anti-angiogenic potential of trypsin inhibitor purified from Cucumis melo seeds: Homology modeling and molecular docking perspective

Keywords: BSA; bovine serum albumin; DMEM; Dulbecco's modified eagle's medium; BBI; Bowman-Birk inhibitor; ELISA; enzyme-linked immunosorbent assay; FBS; fetal bovine serum; HUVEC; human umbilical vein endothelial cells; LDH; lactate dehydrogenase; MTT; 3-(4,5-

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Kinetic and structural characterization of a cis-3-Chloroacrylic acid dehalogenase homologue in Pseudomonas sp. UW4: A potential step between subgroups in the tautomerase superfamily

Keywords: Tautomerase superfamily; 4-Oxalocrotonate tauomerase; cis-3-Chloroacrylic acid dehalogenase; 2-Oxo-3-pentynoate; Evolution; cis-CaaD; cis-3-chloroacrylic acid dehalogenase; CHES; N-Cyclohexyl-2-aminoethanesulfonic acid; DEAE; diethyl-aminoethyl; LB; Luria

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2017 سفارش ترجمه

Structural analysis and insight into Zika virus NS5 mediated interferon inhibition

Keywords: ZIKV; Zika virus; NS5; non-structural protein 5; SIAH2; seven in absentia homolog 2; STAT2; Signal Transducer and Activator of Transcription 2; MTase; methyltransferase; IFN; interferon; IRF9; Interferon Regulatory Factor 9; ISGF3; Interferon-Stimulated G

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

Molecular cloning of ESR2 and gene expression analysis of ESR1 and ESR2 in the pituitary gland of the Chinese alligator (Alligator sinensis) during female reproductive cycle

Keywords: ESRs; estrogen receptors; ERα/ESR1; estrogen receptor alpha; ERβ/ ESR2; ESTROGEN receptor beta; cDNA; DNA complementary to RNA; mRNA; Messenger RNA; PCR; polymerase chain reaction; RT; reverse transcription; qPCR; quantitative real-time PCR; 3D; three d

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

The key residue within the second extracellular loop of human EP3 involved in selectively turning down PGE2- and retaining PGE1-mediated signaling in live cells

Keywords: EP selectivity; G protein-coupled receptor (GPCR); Prostaglandin; Prostaglandin E1; Prostaglandin E2; Receptor regulation; AA; arachidonic acid; COX-1 and -2; cyclooxygenase-1 and -2, respectively; cPGES; cytosolic PGES; DGLA; dihomo-γ-linolenic acid; EP

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

In vivo effects of metal ions on conformation and mechanical performance of silkworm silks

Keywords: ASG; anterior silk gland; CD; circular dichroism; CDS; coding sequence; EST; expressed sequence tag; FTIR; Fourier-transform infrared spectroscopy; ICP-AAS; inductively coupled plasma atomic absorption spectroscopy; MSG; middle silk gland; NCBI; National

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2017 سفارش ترجمه

Design, synthesis and evaluation of scutellarein-O-acetamidoalkylbenzylamines as potential multifunctional agents for the treatment of Alzheimer's disease

Keywords: Alzheimer's disease; Scutellarein-O-acetamidoalkylbenzylamines; Multifunctional agents; Acetylcholinesterase inhibitors; Aβ aggregation inhibitors; Antioxidant agents; AD; Alzheimer's disease; AChE; acetylcholinesterase; ACh; acetylcholine; Aβ; β-amylo

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2017 سفارش ترجمه

Mechanisms of protection against irreversible oxidation of the catalytic cysteine of ALDH enzymes: Possible role of vicinal cysteines

Keywords: Cysteine conformers; ALDHs catalytic loop; Catalytic Cys pKa; Sulfenic acid; Disulfide bond; Residue conservation; ALDH; aldehyde dehydrogenase; BME; 2-mercaptoethanol; DTT; 1,4-dithiothreitol; GSH; reduced glutathione; HsALDH2; mature human ALDH2; PDB; P

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2017 سفارش ترجمه

Structure, function, and mechanism of proline utilization A (PutA)

Keywords: Flavoprotein; Flavin-dependent reaction; Protein structure; proline catabolism; Multifunctional enzymes; Substrate channeling; Aldehyde dehydrogenase; Enzyme hysteresis; ALDH; aldehyde dehydrogenase; ALDHSF; aldehyde dehydrogenase superfamily; BbPutA; Bde

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of novel dengue virus NS5 methyltransferase non-nucleoside inhibitors by fragment-based drug design

Keywords: Phenyl [(phenylcarbamoyl)amino]benzene-1-sulfonate derivatives; N-Phenyl-[(phenylcarbamoyl)amino]benzene-1-sulfonamide derivatives; Fragment-linking strategy; Dengue virus; NS5 methyltransferase inhibitors; Antiviral activity; DENV; dengue virus; NS; non-

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2017 سفارش ترجمه

The MPN domain of Caenorhabditis elegans UfSP modulates both substrate recognition and deufmylation activity

Keywords: UfSP; Ufm1; MPN domain; Deufmylation; Crystal structure; Ufm1; Ubiquitin-fold modifier 1; UfSP; Ufm1 specific protease; cUfSP; UfSP from C. elegans; UBL; ubiquitin-like protein; ER; endoplasmic reticulum; MPN; Mpr1p and PAD1p N-terminal; UfBP1; Ufm1 bindi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Production of a soluble single-chain variable fragment antibody against okadaic acid and exploration of its specific binding

Keywords: Okadaic acid; CLEIA; Single-chain variable fragment; Binding complex; OA; okadaic acid; DSP; diarrhetic shellfish poisoning; ELISA; enzyme-linked immunosorbent assay; scFv; single-chain variable fragment; CDR; complementarity-determining region; PDB; Prot

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

ALS-FTLD associated mutations of SQSTM1 impact on Keap1-Nrf2 signalling

Keywords: ALS; Amyotrophic lateral sclerosis; ARE; Antioxidant response element; FTLD; Frontotemporal lobar degeneration; IKKβ; Inhibitor of nuclear factor kappa-B kinase subunit beta; Keap1; Kelch-like ECH-associated protein 1; KIR; Keap1-interacting region; LIR;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Web-based volume slicer for 3D electron-microscopy data from EMDB

Keywords: CSS; Cascading Style Sheets; DOM; Document Object Model; EMDB; Electron Microscopy Data Bank; EBI; European Bioinformatics Institute; NMR; Nuclear Magnetic Resonance; OME; Open Microscopy Environment; OMERO; OME Remote Objects; PDB; Protein Data Bank; PDB

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

The unusual substrate specificity of a virulence associated serine hydrolase from the highly toxic bacterium, Francisella tularensis

Keywords: DSF; differential scanning fluorimetry; FTT0941c; virulence associated serine hydrolase from Francisella tularensis; HSL; hormone sensitive lipase; KEGG; Kyoto Encyclopedia of Genes and Genomes; LB; Luria-Bertani broth; MWCO; molecular weight cut-off; Ni-

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Crystal structure of the enzyme-product complex reveals sugar ring distortion during catalysis by family 63 inverting α-glycosidase

Keywords: EcYgjK; Escherichia coli YgjK; GH63; glycoside hydrolase family 63; Glc1,2Gal; 2-O-α-d-glucopyranosyl-d-galactose; β-GlcF; β-glucopyranosyl fluoride; PDB; Protein Data Bank; RMSD; root mean squared deviation; Glycoside hydrolase family 63; Inverting me

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Establishment of a human indoleamine 2, 3-dioxygenase 2 (hIDO2) bioassay system and discovery of tryptanthrin derivatives as potent hIDO2 inhibitors

Keywords: Indoleamine 2; 3-dioxygenase 2; IDO2 bioassay system; IDO2 inhibitor; Tryptanthrin derivatives; hIDO2; human indoleamine 2, 3-dioxygenase 2; IDO1; indoleamine 2, 3-dioxygenase 1; L-1-MT; L-1-methyl-tryptophan; TDO; tryptophan 2, 3-dioxygenase; LLC; Lewis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Evaluation of in vitro and in vivo anti-inflammatory effects of (−)-pseudosemiglabrin, a major phytoconstituent isolated from Tephrosia apollinea (Delile) DC

Keywords: ANOVA; Analysis Of Variance; COX; Cyclooxygenase; DMSO; Dimethyl Sulfoxide; ELISA; Enzyme-Linked Immunosorbent Assay; IgG; Immunoglobulin G; IFN-α, -γ; Interferon-alpha, gamma; IL-1; Interlukin-1; LPS; lipopolysaccharide; NO; nitric oxide; µ-OR; opioid

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Identification of the two-phase mechanism of arachidonic acid regulating inflammatory prostaglandin E2 biosynthesis by targeting COX-2 and mPGES-1

Keywords: Arachidonic acid; Cyclooxygenase-2; Microsomal prostaglandin E2 synthase; Polyunsaturated fatty acid; Prostaglandin E2; 10aa; 10 amino acid residues; AA; arachidonic acid; CHD; coronary heart disease; COX-1 and -2, respectively; cyclooxygenase-1 and -2; c

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Kinetic, thermodynamic and structural analysis of tamiphosphor binding to neuraminidase of H1N1 (2009) pandemic influenza

Keywords: Influenza neuraminidase; Oseltamivir; Tamiphosphor; Isothermal titration calorimetry; Crystal structure; Lattice-translocation defect; 4-MUNANA; 2′-(4-methylumbelliferyl)-α-d-N-acetylneuraminic acid; NA; neuraminidase; PDB; protein data bank; ITC; isot

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Gypsy moth pheromone-binding protein-ligand interactions: pH profiles and simulations as tools for detecting polar interactions

Keywords: Gypsy moth; Olfaction; Ligand interactions; Pheromone-binding protein; Homology modeling; pH profile of ligand binding; (−)-Dis; (−)-disparlure = (7S, 8R)-epoxy-2-methyloctadecane; (+)-Dis; (+)-disparlure = (7R, 8S)-epoxy-2-methyloctadecane; ANOVA

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Lipases from the genus Rhizopus: Characteristics, expression, protein engineering and application

Keywords: ROL; R. oryzae lipase; RCL; R. chinensis lipase; RSL; R. stolonifer lipase; RML; Rhizomucor miehei lipase; mROL; the mature R. oryzae lipase; ProROL; the R. oryzae prolipase; r28ROL; the mature R. oryzae lipase containing 28 amino acids of the prosequence

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Development and Characterization of FLT3-Specific Curcumin-Loaded Polymeric Micelles as a Drug Delivery System for Treating FLT3-Overexpressing Leukemic Cells

Keywords: targeted drug delivery; micelle; peptides; polymeric drug delivery systems; nanoparticle; CM; curcumin; FLT3; Feline McDonough Sarcoma (FMS)-like tyrosine kinase 3; P407; poloxamer 407; PDB; protein data bank;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Adhesion GPCRs in immunology

Keywords: GPCR; G protein-coupled receptor; aGPCR; adhesion G protein-coupled receptor; ADGR; general adhesion GPCR name followed by class and subtype specific code; 7TM; 7 transmembrane; VLGR1; very large G protein-coupled receptor 1; ECD; extracellular domain; GP

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Comparative genomics study for identification of putative drug targets in Salmonella typhi Ty2

Keywords: S. typhi; Salmonella typhi; KEGG; Kyoto Encyclopedia of Genes and Genomes; DEG; Database of Essential Genes; WHO; World Health Organization; PDB; Protein Data Bank; NCBI; National Center for Biotechnology Information; MDRTF; Multi-Drug Resistance Typhoid

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Contribution of bacteriochlorophyll conformation to the distribution of site-energies in the FMO protein

Keywords: AHC; agglomerative hierarchical clustering; BChl; bacteriochlorophyll; Chl; chlorophyll; E(BChl)cryst; in vacuo SPE of BChl in protein bound conformation; ΔQy[Mac]; site-energy perturbation due to macrocycle distortion; dip; mean absolute deviation of NS

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

The Chromatin Remodelling Protein CHD1 Contains a Previously Unrecognised C-Terminal Helical Domain

Keywords: PDB; protein data bank; CHD; chromodomain helicase DNA-binding protein; ISWI; imitation switch; CHCT; CHD1 helical C-terminal domain; EMSA; electrophoretic mobility shift assay; PNK; polynucleotide kinase; HMM; hidden Markov model; NOE; nuclear Overhauser

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

Establishment of correlation between in-silico and in-vitro test analysis against Leishmania HGPRT to inhibitors

Keywords: HGPRT; hypoxanthine-guanine phosphoribosyltransferase; HPRT; hypoxanthine phosphoribosyltransferase; APRT; adenosine phosphoribosyltransferase; XPRT; xanthine phosphoribosyltransferase; CL; cutaneous leishmaniasis; MCL; muco-cutaneous leishmaniasis; VL; v

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2016 سفارش ترجمه

The RNA 3D Motif Atlas: Computational methods for extraction, organization and evaluation of RNA motifs

Keywords: HL; Hairpin Loop; IL; Internal Loop; 3WJ; 3-way Junction; 4WJ; 4-way Junction; MHJ; Multi-Helix Junction; 2D structure; Secondary structure; PDB; Protein Data Bank; NDB; Nucleic Acid Database; WC; Watson-Crick; non-WC; non-Watson-Crick; BP; basepair; NR;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2016 سفارش ترجمه

Salmonella enterica serovar Typhimurium growth is inhibited by the concomitant binding of Zn(II) and a pyrrolyl-hydroxamate to ZnuA, the soluble component of the ZnuABC transporter

Keywords: SeZnuA; Salmonella enterica ZnuA; RDS library; Roberto Di Santo library; PDB; Protein Data Bank; ZnuA; ZnuABC zinc transporter; Salmonella enterica; X-ray structure; Lead compounds;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2016 سفارش ترجمه

In-silico structural analysis of E509K mutation in LARGE and T192M mutation in Alpha Dystroglycan in the inhibition of glycosylation of Alpha Dystroglycan by LARGE

Keywords: DMD; Duchenne Muscular Dystrophy; α-DG; Alpha Dystroglycan; DAPC; Dystrophin Associated Protein Complex; MDDGC9; Muscular Dystrophy Dystroglycanopathy type C9; OMIM; Online Mendelian Inheritance in Man; EC; Enzyme Commission number; MDDGB6; Muscular Dyst

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2016 سفارش ترجمه

A promiscuous recognition mechanism between GPR17 and SDF-1: Molecular insights

Keywords: SDF-1; stromal cell-derived factor 1; GPCR; G protein-coupled receptor; CNS; central nervous system; NS; nervous system; DRG; dorsal root ganglion; OPC; oligodendrocyte precursor cell; MS; multiple sclerosis; PDB; Protein Data Bank; TM; transmembrane; EL;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2016 سفارش ترجمه

Reversible oxidation controls the activity and oligomeric state of the mammalian phosphoglycolate phosphatase AUM

Keywords: CD; circular dichroism; DTT; dithiothreitol; EGF; epidermal growth factor; G3P; glycerol-3-phosphate; HAD; haloacid dehalogenase; IAA; iodoacetic acid; IAP; iodoacetyl polyethylene glycol; LDH; lactate dehydrogenase; MALS; multi angle light scattering; PD

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2016 سفارش ترجمه

Highlights on Hevea brasiliensis (pro)hevein proteins

Keywords: Hevein; Prohevein; Hev b 6 latex allergens; Natural rubber; Antimicrobial peptides; Plant amyloids; Hb; Hevea brasiliensis (Hevea); ATR-FTIR; attenuated-total reflectance Fourier-transform infra-red; SRP; small rubber particle; LRP; large rubber particle;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

Structural and biochemical characterization of bacterial YpgQ protein reveals a metal-dependent nucleotide pyrophosphohydrolase

Keywords: HD; histidine-aspartate; (d)NTP; (deoxy)ribonucleoside triphosphate; bsYpgQ; Bacillus subtilis YpgQ; dNTP; deoxyribonucleoside triphosphate; NTP; ribonucleoside triphosphate; dNMP; deoxyribonucleoside monophosphate; Pi; inorganic monophosphate; PPi; inorg

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه