کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2019080 | 1542166 | 2016 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Lipases from the genus Rhizopus: Characteristics, expression, protein engineering and application
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کلمات کلیدی
PAOXRCLMLMpNPPPGAPRSLTLFBDO-statPDBSMFRMLEnantioselectivitySSFHuman milk fat substitutesp-Nitrophenyl palmitateHeterologous expression - بیان هترولوژیکBiodiesel - بیودیزلSolid-state fermentation - تخمیر جامدSubmerged fermentation - تخمیر زیرزمینیCharacterization - تعیین مشخصاتdiglyceride - دیالیزرایدROL - رولLipase - لیپازRhizomucor miehei lipase - لیپاز ریزوموکور مایدیMethyl ester - متیل استرBioengineering - مهندسی زیستیmonoglyceride - مونوگلیسیریدProtein Data Bank - پروتئین بانک اطلاعاتیDissolved oxygen control - کنترل اکسیژن حل شده
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
دانش تغذیه
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Lipases are versatile catalysts that hydrolyze ester bonds of water-insoluble glycerides or carry out reversible reactions at the water/lipid interface. The remarkable characteristics of lipases from the genus Rhizopus are their high sn-1,3-positional specificity, enantioselectivity and activity in nonaqueous media, which make them one of the most desirable enzymes for many applications, including lipid modification and biodiesel and chiral organic compound synthesis. sn-1,3-Position-specific Rhizopus lipases are particularly useful for the production of structured triacylglycerols. Significant progress has been made regarding lipases from the genus Rhizopus, including gene sequencing, elucidation of the protein structure and catalytic function, heterologous expression and redesigning Rhizopus lipases for valuable properties, which is receiving increasing academic and industrial attention. In this review, we present a comprehensive overview of Rhizopus lipases, focusing on (a) the characteristics of Rhizopus lipases, (b) Rhizopus lipase genes and structural features, (c) strategies for heterologous expression of Rhizopus lipase genes in yeast system, (d) progress in protein engineering for the improvement of the properties of Rhizopus lipases, and (e) development of biotechnological applications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Progress in Lipid Research - Volume 64, October 2016, Pages 57-68
Journal: Progress in Lipid Research - Volume 64, October 2016, Pages 57-68
نویسندگان
Xiao-Wei Yu, Yan Xu, Rong Xiao,