دانلود مقالات ISI درباره Pdb + ترجمه فارسی

Identification of a novel mutation (Ala66Thr) of SRY gene causes XY pure gonadal dysgenesis by affecting DNA binding activity and nuclear import

Keywords: AR; androgen receptor; CYP11A1; cytochrome P450 family 11 subfamily a member 1; CYP17A1; cytochrome P450 family 17 subfamily a member 1; DHH; desert hedgehog; DMRT1/2/3; doublesex and mab-3 related transcription factor 1/2/3; DSD; disorders of sex develop

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Peculiar genes for thermostable bifunctional catalase-peroxidases in Chaetomium thermophilum and their molecular evolution

Keywords: CDS; coding sequence; GB; GenBank; katG; gene coding for a bifunctional catalase-peroxidase; HGT; horizontal gene transfer; ML; maximum likelihood phylogenetic method; PDB; protein data bank; PolA; polyadenylation site; ROS; reactive oxygen species; RT-qP

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Piriformospora indica cell wall extract as the best elicitor for asiaticoside production in Centella asiatica (L.) Urban, evidenced by morphological, physiological and molecular analyses

Keywords: Piriformospora indica cell wall extract; Centella asiatica; HPLC; β amyrin synthase; MJ; Methyl Jasmonate; DMSO; Methyl Sulfinyl Methane; AM; Arbuscular Mycorrhiza; DSM; Deutsche Sammlung fur Mikroorganismen; PiCWE; P. indica Cell Wall Extract; SQS; Squa

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Structural basis for the substrate recognition of peptidoglycan pentapeptides by Enterococcus faecalis VanYB

Keywords: VRE; vancomycin-resistant Enterococcus; NAM; N-acetylmuramic acid; NAG; N-acetylglucosamine; PEG; polyethylene glycol; SAD; single-wavelength anomalous diffraction; RMSD; root-mean-square deviation; SEC-MALS; size-exclusion chromatography with multi-angle

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Extract from Butea monosperma inhibits β-catenin/Tcf signaling in SW480 human colon cancer cells

Keywords: CRC; colorectal cancer; NBF-BMFE; n-butanol fraction of B. monosperma flower extract; APC; adenomatous polyposis coli; GSK-3β; glycogen synthase kinase 3β; CK1; casein kinase 1; LRP5/6; low density lipoprotein receptor- related protein; Dvl; dishevelled

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

The evaluation of potent antitumor activities of shikonin coumarin-carboxylic acid, PMMB232 through HIF-1α-mediated apoptosis

Keywords: HIF-1α; hypoxia-inducible factor alpha 1; DMAP; 4 dimethyamino- pyridine; DCC; N, N' dicyclohexylcarbodiimide; DMEM; Dulbecco's modified Eagle's medium; MTT; 3-(4 5-dimethyl-2-thiazolyl)-2 5-diphenyl-2-H-tetrazolium bromide; IC50; Half of maximal i

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Insights into the carbonic anhydrases and autotrophic carbon dioxide fixation pathways of high CO2 tolerant Rhodovulum viride JA756

Keywords: 'C'; carbon; 3-HP; 3-hydroxypropionate; 4-HB; 4-hydroxybutyrate; ACL; ATP-citrate lyase; ADP; adenosine diphosphate; CA; carbonic anhydrase; CBB; Calvin-Benson-bassham; CCL; citryl-CoA lyase; CCM; carbon concentrating mechanism; CCS; citryl-CoA synthe

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Molecular and in silico analyses validates pathogenicity of homozygous mutations in the NPR2 gene underlying variable phenotypes of Acromesomelic dysplasia, type Maroteaux

Keywords: AMDM; Acromesomelic dysplasia, Maroteaux type; ECD; extracellular domain; GC; guanylate cyclase; CNP; C-type natriuretic peptide; PDB; protein databank; PDF; probability density function; DOPE; discrete optimized protein energy; MD; molecular dynamics; Hs

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Regiospecificity of a novel bacterial lipoxygenase from Myxococcus xanthus for polyunsaturated fatty acids

Keywords: LOX; lipoxygenase; PUFA; polyunsaturated fatty acid; HpFA; hydroperoxy fatty acid; HFA; hydroxy fatty acid; LA; linoleic acid; ALA; α-linolenic acid; GLA; γ-linolenic acid; ARA; arachidonic acid; EPA; eicosapentaenoic acid; DHA; docosahexaenoic acid; HO

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Domain swapping dissection in Thermotoga maritima arginine binding protein: How structural flexibility may compensate destabilization

Keywords: TmArgBP; arginine binding protein isolated from Thermotoga maritima; TmArgBP20-233; truncated form of TmArgBP; arg-TmArgBP20-233; arginine-bound form of TmArgBP20-233; lf-TmArgBP20-233; ligand-free form of TmArgBP20-233; TmArgBP_C-ter232-246; peptide corr

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Targeting phosphatases of regenerating liver (PRLs) in cancer

Keywords: Protein tyrosine phosphatase; Metastasis; Theinopyridone; Structure; CBS; cystathionine-beta-synthase; CHO; Chinese hamster ovary; CNNM; magnesium transporters of cyclin M; EMT; epithelial-mesenchymal transition; HMVEC; human microvascular endothelial c

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Network and structure based inference of functional single nucleotide polymorphisms associated with the TGFβ1 gene and its role in colorectal cancer (CRC)

Keywords: CRC; colorectal cancer; TGFβ1; transforming growth factor-β1; MAPK; mitogen-activated protein kinases; PKC; protein kinase C; SNPs; single nucleotide polymorphisms; TFs; transcription factors; NCBI; National Center for Biotechnology Information; ns-SNPs

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Structural model, functional modulation by ivermectin and tissue localization of Haemonchus contortus P-glycoprotein-13

Keywords: Nematode; Haemonchus contortus; ABC transporters; P-glycoprotein; Ivermectin; Homology modeling; ABC; ATP-binding cassette; ACD; actinomycin D; AH; anthelmintic; BlastP; protein Basic Local Alignment Search Tool; bp; base pairs; Cel; Caenorhabditis elegan

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Conserved structure and function of chemokine CXCL8 between Chinese tree shrews and humans

Keywords: CXCL8; chemokine (C-X-C) ligand 8; CXCR1; C-X-C motif chemokine receptor 1; CXCR2; C-X-C motif chemokine receptor 2; Ts; tree shrew; 3D; three-dimensional; PBMCs; peripheral blood mononuclear cells; MHC; major histocompatibility complex; IL-2; interleukin

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Co-chaperon p23 inhibitors: Identification of anticancer compounds from traditional Chinese medicine database

Keywords: Hsp; heat shock protein; TCM; Traditional Chinese Medicine; VS; virtual screening; PDB; Protein Data Bank; Co-chaperon p23; Anticancer; TCM compounds; Hsp90; Apoptosis; Virtual screening;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

Identification of small molecule activators for ErbB 4 receptor to enhance oligodendrocyte regeneration by in silico approach

Keywords: ADMET; adsorption distribution metabolism excretion toxicity; BBB; blood brain barrier; BS; bioavailability score; CNS; central nervous system; CT; C-terminal tail; ECD; extracellular domain; EGF; epidermal growth factor; ESOL; estimated solubility; EV; E

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

Insights into the aquaporin 4 of zebrafish (Danio rerio) through evolutionary analysis, molecular modeling and structural dynamics

Keywords: AQPs; Aquaporins; zAQP4; Zebrafish Aquaporin4; NMO; Neuromyelitis optica; PDB; Protein Data Bank; BLAST; Basic Local Alignment Search Tool; RMSD; Root-Mean-Square Deviation; TM score; Template Modeling score; MD; Molecular Dynamics; VMD; Visual Molecular

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

Design, synthesis, and evaluation of carboxyl-modified oseltamivir derivatives with improved lipophilicity as neuraminidase inhibitors

Keywords: NA; neuraminidase; OS; oseltamivir; OC; oseltamivir carboxylate; TFA; trifluor-oacetic acid; HATU; 1-[bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyr-idinium 3-oxid hexafluorophosphate; DIPEA; N,N-diisopropylethylamine; PDB; protein data bank; In

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

Top surface blade residues and the central channel water molecules are conserved in every repeat of the integrin-like β-propeller structures

Keywords: PDB; Protein Data Bank; Vgb; virginiamycin B lyase; WDR5; WD repeat-containing protein 5; Protein; Structure; Beta-propeller; Repeat; Surface; Water;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

Computational analysis of deleterious SNPs of SLC45A2 involved in oculocutaneous albinism type 4

Keywords: SNP; Single nucleotide polymorphism; SLC45A2; Solute carrier family 45, member 2; OCA4; Oculocutaneous albinism Type 4; nsSNP; Non-synonymous single nucleotide polymorphism; OA; Ocular albinism; TYR; Tyrosinase; TYRP1; Tyrosinase related protein 1; MATP;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2018 سفارش ترجمه

Scaffold hopping identifies 6,8-disubstituted purines as novel anaplastic lymphoma kinase inhibitors

Keywords: ALK; anaplastic lymphoma kinase; cMet; hepatocyte growth factor receptor; DIPEA; N,N-Diisopropylethylamine; DMF; N,N-Dimethylformamide; EML4; echinoderm microtubule-associated protein-like 4; FDA; food and drug administration; gk; gatekeeper; μW; micro w

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Evaluation of morpho-physiological growth parameters of tomato in response to Cd induced toxicity and characterization of metal sensitive NRAMP3 transporter protein

Keywords: Cd; cadmium; ROS; reactive oxygen species; DW; dry weight; FW; fresh weight; SVI; seedling vigor index; TI; tolerance indices; DAB-HCl; diaminobenzidine tetrahydrochloride hydrate; TCA; trichloroacetic acid; H2O2; hydrogen peroxide; Chl; chlorophyll; RT-P

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

New developments in non-quinolone-based antibiotics for the inhibiton of bacterial gyrase and topoisomerase IV

Keywords: Bacterial gyrase; Topoisomerase IV; Drug resistance; Binding sites; Potency; DNA; deoxyribonucleic acid; ATP; adenosine triphosphate; GyrA; gyrase A subunit; GyrB; gyrase B subunit; ParC; topoisomerase IV C subunit; ParE; topoisomerase IV E subunit; PDB;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Inhibitory effects and structural insights for a novel series of coumarin-based compounds that selectively target human CA IX and CA XII carbonic anhydrases

Keywords: Coumarins; hCAs; hCA IX; hCA XII; Antitumor agents; Molecular docking; hCA; human Carbonic Anhydrases; AAZ; acetazolamide; MBG; metal binding groups; CARP; CA related-proteins; SG; sticky group; PDB; RCSB Protein Data Bank;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

The K-path entrance in cytochrome c oxidase is defined by mutation of E101 and controlled by an adjacent ligand binding domain

Keywords: bovCcO; CcO from bovine (Bos taurus); CcO; cytochrome c oxidase; COVs; cytochrome c oxidase-containing lipid vesicles; DDM; dodecyl (lauryl) maltoside; DHA; docosahexaenoic acid; DM; decyl maltoside; DOC; deoxycholate; FCCP; carbonyl cyanide-4-(trifluorom

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Modification of quaternary structure of Candida albicans GlcN-6-P synthase and its desensitization to inhibition by UDP-GlcNAc by site-directed mutagenesis

Keywords: Candida albicans; Glucosamine-6-phosphate synthase; Quaternary structure; UDP-GlcNAc; Site-directed mutagenesis; DTT; dithiothreitol; Fru-6-P; d-fructose-6-phosphate; GAH; glutamine amidohydrolase domain; GlcN-6-P; d-glucosamine-6-phosphate; ISOM; ketose/

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Identification of small-molecule ligands that bind to MiR-21 as potential therapeutics for endometriosis by screening ZINC database and in-vitro assays

Keywords: miR-21; MicroRNA-21; GO; gene ontology; PDB; protein data bank; PMF; potential of mean force; 2AP; analog 2-aminopurine; microRNA-21; Small-molecule ligand; Drug design; Endometriosis;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Phytoestrogens and mycoestrogens interacting with breast cancer proteins

Keywords: AUC; area under the curve; BRCA1; breast cancer 1; BRCA2; breast cancer 2, CAT, catalase; DHT; dihydrotestosterone; EDCs; endocrine disrupting chemicals; ERBB2; human epidermal growth factor receptor 2; ERBBs; epidermal growth factor receptor family; ER-b

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Screening for inhibitory activity of essential oils on fungal tomato pathogen Stemphylium solani Weber

Keywords: AC; Aloysia citrodora; AL; Aloysia lycioides; BP; Baccharis psiadioides; BT; Baccharis trimera; BA; Baccharis articulata; BO; Baccharis ochraceae; CC; Cinnamomum camphora var. linaloolifera; EG; Eucalyptus globulus; ES; Eucalyptus staigeriana; FV; Foenicu

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Conservation and variation of the hepatitis E virus ORF2 capsid protein

Keywords: HEV; hepatitis E virus; ORF; open reading frames; AA; amino acid; ICTV; International Committee on Taxonomy of Virus; PDB; Protein Data Bank; RMSD; root mean square deviation; VLP; virus-like particles; mAb; monoclonal antibody; MW; molecular weight; NCBI

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Classification of β-hairpin repeat proteins

Keywords: 3D; three-dimensional; BHR; β-hairpin repeat; H-bond; hydrogen bond; PDB; Protein Data Bank; Beta-structure; Beta-barrel; Porin; Proteins with repeats; Structural classification; Sequence-structure relationship;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Assessment of detailed conformations suggests strategies for improving cryoEM models: Helix at lower resolution, ensembles, pre-refinement fixups, and validation at multi-residue length scale

Keywords: EMDB; Electron Microscopy Data Base; PDB; Protein Data Bank; Tx yyy_z, or T000xEMyyy_z; Target x model yyy_z, the zth submitted model for Challenge target x from modeling group yyy (e.g., T0001EM123_2); H-bond; hydrogen-bond; CaBLAM; Calpha-Based Low-reso

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Antifungal activity of Latarcin 1 derived cell-penetrating peptides against Fusarium solani

Keywords: AMP; Antimicrobial peptide; CPP; Cell-penetrating peptide; CLSM; Confocal laser scanning microscopy; FACS; Fluorescence-activated cell sorter; FITC; Fluorescein isothiocyanate; LD; Latarcin derivatives; LDP; Latarcin derived peptide; MAP; Membrane-active

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Identification of Isomeric Aspartate residues in βB2-crystallin from Aged Human Lens

Keywords: DTT; dithiothreitol; EDTA; ethylendiaminetetraacetic acid; PDB; Protein Data Bank; PMSF; phenylmethanesulfonyl fluoride; SIM; selective ion monitoring; Asp isomerization; Cataract; β-crystallin; Post-translational modification; Protein aggregation; LC-MS

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Association and in silico studies of ENPP1 gene variants with type 2 diabetes mellitus in a Northern Iranian population

Keywords: DM; diabetes mellitus; T2DM; type 2 diabetes mellitus; GWAS; genome-wide association studies; SNP; single nucleotide polymorphism; ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase 1; UTR; Untranslated Region; K; lysine; Q; glutamine; ATP; Adenosine

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Pore-forming mechanism of TUBP1 protein act on Verticillium dahliae

Keywords: PDA; potato dextrose agar; PDB; potato dextrose broth; MIC; minimum inhibitory concentration; PI; propidium iodide; FDs; FITC-labeled dextrans; DiSC35; 3,3`-dipropylthiacarbocyanine; FITC; fluorescein isothiocyanate; LUVs; large unilamellar vesicles; TUBP

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction

Keywords: Anti-Influenza; PA-PB1; RdRp; Amino acid coupling; SPPS; Diphenyl-pyridine; AcOEt; Ethyl acetate; CC50; Half maximal cytotoxic concentration; cRNA; complementar RNA; DCM; dichloromethane; DDQ; 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone; DIPEA; N,N-Diisopro

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

An integrated computational hierarchy for identification of potent inhibitors against Shikimate Kinase enzyme from Shigella sonnei, a major cause of global dysentery

Keywords: ATP; adenosine triphosphate; SK; Shikimate Kinase; PDB; Protein Data Bank; GOLD; Genetic Optimization for Ligand Docking; VMD; Visual Molecular Dynamics; DS; Discovery Studio; PRDOS; Protein DisOrder prediction System; PK; pharmacokinetics; BBB; blood-bra

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Improving the thermostability of Serratia marcescens B4A chitinase via G191V site-directed mutagenesis

Keywords: DNS; 3, 5-dinitrosalicylic acid; PDB; Protein Data Bank; WT; wild type; QCSDM; quick-change site-directed mutagenesis; IPTG; isopropyl-c-D-thiogalactoside; Km; Michaelis constant; Vmax; maximum velocity; RMSD; root-mean-square deviation; β chain; Chitina

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Crystal structure of the Eg5 - K858 complex and implications for structure-based design of thiadiazole-containing inhibitors

Keywords: 1,3,4-thiadiazole; K858 enantiomers; Eg5; Antimitotic drugs; Eg5-K858 complex; Rational drug design; KSP; Kinesin spindle protein; MT; Microtubule; PDB; Protein Data Bank; PK; Pyruvate kinase; LDH; Lactate dehydrogenase; ITC; Isothermal titration calorime

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Assessing GPCR homology models constructed from templates of various transmembrane sequence identities: Binding mode prediction and docking enrichment

Keywords: A2AAR; adenosine receptor A2A; AUC; area under curve; β2AR; beta 2 adrenergic receptor; D3R; dopamine receptor D3; δOR; delta-opioid receptor; ECL; extracellular loop; GPCR; G protein-coupled receptor; H1R; histamine receptor H1; ICL; intracellular loop

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Intrinsic structural versatility of the highly conserved 412-423 epitope of the Hepatitis C Virus E2 protein

Keywords: HCV; Hepatitis C Virus; E2; envelope glycoprotein 2; CD81; Cluster of Differentiation 81; ThT; Thioflavin T; PDB; Protein Data Bank; mAb; monoclonal Antibodies; Fab; antigen-binding fragment; MD; molecular dynamics; RMSD; root mean square deviation; RMSIP

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

New aziridine-based inhibitors of cathepsin L-like cysteine proteases with selectivity for the Leishmania cysteine protease LmCPB2.8

Keywords: Cysteine protease; Inhibitor; Aziridine; Rhodesain; Cruzain; Leishmania; DCC; Dicyclohexylcarbodiimide; DMAP; 4-(Dimethylamino)pyridine; DPSI; (S,S)-Diphenylsulfimine; GB/VI methodology; Generalized Born/Volume Integral methodology; LE; ligand efficiency;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

UvrB protein of Corynebacterium pseudotuberculosis complements the phenotype of knockout Escherichia coli and recognizes DNA damage caused by UV radiation but not 8-oxoguanine in vitro

Keywords: BER; base excision repair; BLAST; Basic Local Alignment Search Tool; DOPE; Discrete Optimized Protein Energy; NER; nucleotide excision repair; PDB; Protein Data Bank; Rg; radio of gyration; RMSD; root mean square deviation; RNS; reactive nitrogen species;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Probing the role of Arg97 in Heat shock protein 90 N-terminal domain from the parasite Leishmania braziliensis through site-directed mutagenesis on the human counterpart

Keywords: Heat shock protein 90; Leishmania braziliensis; Protozoan parasites; X-ray crystallography; Selectivity; Nucleotides; LB; Luria Bertani; SB; Super Broth; IPTG; Isopropil-β-D-1-thiogalactopyranoside; DTT; Dithiothreitol; ATP; Adenosine triphosphate; ADP;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

A close look onto structural models and primary ligands of metallo-β-lactamases

Keywords: ADP; atomic displacement parameters (B factors); ASU; asymmetric unit; BLDB; β-Lactamase Data Base; BME; β-mercaptoethanol; EDO; ethylene glycol; EDS; Electron Density Server; MBL; metallo-β-lactamase; MC; main chain; NCS; non-crystallographic symmetry

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Domain communication in Thermotoga maritima Arginine Binding Protein unraveled through protein dissection

Keywords: TmArgBP; wild-type Arginine Binding Protein isolated from Thermotoga maritima; TmArgBP20-233; residues 20-233 of TmArgBP; D1; domain 1 of TmArgBP; D2; domain 2 of TmArgBP; SBP; substrate binding protein; RMSD; root mean square deviation; RMSF; root me

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Computational elucidation of novel antagonists and binding insights by structural and functional analyses of serine hydroxymethyltransferase and interaction with inhibitors

Keywords: SHMT; Serine hydroxymethyltransferase; Ld; Leishmania donovani; PLP; Pyridoxal phosphate; THF; Tetrahydrofolate; TS; Thymidylate synthase; PDB; Protein Data Bank; NCBI; National Center for Biotechnology Information; DOPE; Discrete optimized protein energy

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Oroxin A from Oroxylum indicum prevents the progression from prediabetes to diabetes in streptozotocin and high-fat diet induced mice

Keywords: Oroxin A; Prediabetes; Type 2 diabetes; PPARγ; Mechanism; 2h-PG; 2-h postprandial glucose; ALT; alanine transaminase; AST; aspartate transaminase; AUC; area under the curve; CMC-Na; Sodium carboxymethylcellulose; CαRMSD; Cα root mean square deviation;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Copper(II)-sulfonamide Schiff base complexes: Structure, biological activity and theoretical interpretation

Keywords: ADMET; adsorption, distribution, metabolism, excretion, toxicity in pharmacokinetics; B3LYP; becke, three parameters, Lee-Yang-Parr; DFT; density functional theory; DHPS; dihydropteroate synthase; PDB; protein data bank; SMX; Sulfamethoxazole; STZ; Sulfat

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه