دانلود مقالات ISI درباره Pdb + ترجمه فارسی

Cytoprotection of lipoic acid against toxicity induced by saxitoxin in hippocampal cell line HT-22 through in silico modeling and in vitro assays

Keywords: ARE; antioxidant response element; BBB; blood brain barrier; CNS; central nervous system; dc-STX; dc-saxitoxin; DFT; density functional simulation; DHLA; dihidrolipoic acid; DMEM; Dulbenco's Modified Eagles Medium containing high glucose; DMSO; dimetils

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Degradation of fibrin-β amyloid co-aggregate: A novel function attributed to ubiquitin

Keywords: AD; Alzheimer disease; AFM; atomic force microscopy; CAA; cerebral amyloid angiopathy; CHCA; α-cyano-4-hydroxycinnamic acid; DAPI; 4′,6-diamidino-2-phenylindole; DMEM; Dulbecco's modified eagle medium; DMSO; dimethyl sulfoxide; ELISA; enzyme-linked imm

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

NMR structures in different membrane environments of three ocellatin peptides isolated from Leptodactylus labyrinthicus

Keywords: BHK; 21 baby hamster kidney cells; CD; circular dichroism; DD K; dermadistinctin K; DPC; dodecylphosphorylcholine; DPC-d38; dodecylphosphorylcholine-d38; DSS; sodium 2,2-dimethyl-2-silapentane-5-sulfonate; Fmoc; fluorenylmethyloxycarbonyl; Gly; glycine; 1

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Highly stable single-strand-specific 3′-nuclease/nucleotidase from Legionella pneumophila

Keywords: 3′-AMP; adenosine 3′‑monophosphate; 5′-AMP; adenosine 5′‑monophosphate; CD; circular dichroism; DTT; 1,4‑dithiotreitol; EDTA; ethylenediaminetetraacetic acid; IEF; isoelectric focusing; LCV; Legionella-containing vacuole; Lp; Legionella pneu

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Acylguanidine derivatives of zanamivir and oseltamivir: Potential orally available prodrugs against influenza viruses

Keywords: Acylguanidine; Zanamivir; Oseltamivir; Neuraminidase inhibitor; Influenza; Arg; arginine; Boc; tert-butoxycarbonyl; (Boc)2O; di(tert-butyl) dicarbonate; CC50; half maximal cytotoxicity concentration; CPE; cytopathic effect; DIEA; diisopropyl ethylamine; D

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Solution NMR views of dynamical ordering of biomacromolecules

Keywords: ALS; Amyotrophic Lateral Sclerosis; CPMG; Carr-Purcell-Meiboom-Gill; CPP; Cell Penetrating Peptide; CHO; Chinese Hamster Ovary Cells; Rex; Chemical/Conformational Exchange; (C)EST; (Chemical) Exchange Saturation Transfer; CSA; Chemical Shift Anisotropy; C

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

E7 oncoprotein of human papillomavirus: Structural dynamics and inhibitor screening study

Keywords: HPV; Human papillomavirus; pRB; Phosphorylated Retiboblastoma; 3D; Three dimensional; MoRFs; Molecular recognition features; DNA; Deoxyribo nucleic acid; CRs; Conserved regions; IDPs; Intrinsically disordered proteins; CD-HIT; Cluster database at high ide

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Bioinformatics analysis of ROP8 protein to improve vaccine design against Toxoplasma gondii

Keywords: Toxoplasma gondii; ROP8; Bioinformatics analysis; Vaccine; 3D; three-dimensional; ACC; auto cross covariance; ANN; artificial neural network; CD; cluster of differentiation; CI; confidence interval; CTL; cytotoxic T lymphocyte; GOR; Garnier-Osguthorpe-Rob

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2018 سفارش ترجمه

Molecular determinants of PPARγ partial agonism and related in silico/in vivo studies of natural saponins as potential type 2 diabetes modulators

Keywords: Type 2 diabetes; Saponins; PPARγ; Partial agonists; Pharmacophore; Docking; CAT; catalase; GSH; reduced glutathione; HB; hydrogen bond; MDA; malondialdehyde; NADPH; beta-nicotinamide adenine dinucleotide 2′-phosphate; PDB; Protein Data Bank; PPARγ;

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2018 سفارش ترجمه

Expression of Cry1Ac toxin-binding region in Plutella xyllostella cadherin-like receptor and studying their interaction mode by molecular docking and site-directed mutagenesis

Keywords: BSA; bovine serum albumin; cDNA; complementary DNA; ELISA; enzyme-linked immunosorbent assay; HRP; horse radish peroxidase; IPTG; isopropyl-beta-d-thiogalactopyranoside; MPBS; PBS containing skim milk; Ni-NTA; nickel-nitrilotriacetic acid; OD; optical den

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2018 سفارش ترجمه

Structure-function study of two new middle-redox potential laccases from basidiomycetes Antrodiella faginea and Steccherinum murashkinskyi

Keywords: 2,6-DMP; 2,6-dimetoxyphenol; ABTS; 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt; EPR; electron paramagnetic resonance; PDB; Protein Data Bank; Laccase; Basidiomycetes; Crystal structure; Redox potential; 3D structure analysis;

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

Lysine as a heme iron ligand: A property common to three truncated hemoglobins from Chlamydomonas reinhardtii

Keywords: 2-over-2 hemoglobin; Heme reduction potential; Nitric oxide dioxygenase; Nuclear magnetic resonance; 1D; one-dimensional; CtrHb; heme domain of Chlamydomonas eugametos LI637 hemoglobin; DEAE; diethylaminoethyl; DQF-COSY; double-quantum filtered correlatio

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2018 سفارش ترجمه

Peramivir conjugates as orally available agents against influenza H275Y mutant

Keywords: Peramivir; Caffeic acid; Conjugate; Neuraminidase; Inhibitor; Influenza; Drug resistance; Ala; alanine; All; allyl; Asn; asparagine; Asp; aspartic acid; CDI; 1,1′-carbonyl diimidazole; DIBAL-H; diisobutylaluminium hydride; DMAP; 4-dimethylaminopyridine;

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2018 سفارش ترجمه

Novel CIL-102 derivatives as potential therapeutic agents for docetaxel-resistant prostate cancer

Keywords: CIL-102 derivatives; CR PCa; Docetaxel-resistant cancer; Anti-microtubule agents; Selectivity; Androgen deprivation therapy; ADT; Androgen-independent; AI; Androgen receptor; AR; Androgen-sensitive; AS; Castration-Resistant Prostate Cancer; CRPC; dichloro

دانلود رایگان متن کامل مقاله ISI 65 صفحه سال انتشار : 2018 سفارش ترجمه

Sedative-hypnotic-like effect and molecular docking of di-naphthodiospyrol from Diospyros lotus in an animal model

Keywords: TLC; thin layer chromatography; S.E.M.; standard error of the mean; DFT; density functional theory; PDB; protein data bank; GABAA; gamma aminobutyric acid; Dimeric napthoquione; Sedative-hypnotic effect; Molecular docking;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

A three-dimensional model of RNase P in the hyperthermophilic archaeon Pyrococcus horikoshii OT3

Keywords: Archaea; Protein-RNA interaction; Pyrococcus horikoshii; Ribonuclease P; Three-dimensional model; 3-D; three-dimensional; C-domain; catalytic domain; CR; conserved region; K-turn; kink-turn; PDB; protein data bank; PhopRNA; Pyrococcus horikoshii ribonucle

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

A pilot study assessing the value of 3D printed molecular modelling tools for pharmacy student education

Keywords: 3D; three-dimensional; ABS; acrylonitrile butadiene styrene; CAD; computer-aided design; PDB; protein data bank; PLA; polylactic acid; RCSB; Research Collaboratory for Structural Bioinformatics; 3D printing; Education; Medicinal chemistry; Molecular model

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

The methicillin-resistant S. epidermidis strain RP62A genome mining for potential novel drug targets identification

Keywords: MRSE; Methicillin resistant Staphylococcus epidermidis.; NCBI; National Center for Biotechnology Information.; H. sapiens; Homo sapiens.; DEG; Database of Essential Genes.; KEGG; Kyoto Encyclopedia of Genes and Genomes.; PDB; Protein Data Bank.; Subtracti

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Piceatannol, a natural trans-stilbene compound, inhibits human glyoxalase I

Keywords: Glyoxalase I; Inhibitor; Stilbenes; Piceatannol; Anticancer; GLO I; Glyoxalase I; BBGC; S-p-bromobenzylglutathione cyclopentyl diester; GSH; glutathione; HIPC-GSH; S-(N-hydroxy-N-indophenylcarbamoyl) glutathione; NSCLC; Non-small cell lung cancer; PDB; Pr

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Stigmatellin Y - An anti-biofilm compound from Bacillus subtilis BR4 possibly interferes in PQS-PqsR mediated quorum sensing system in Pseudomonas aeruginosa

Keywords: BIC; biofilm inhibitory compound(s); LC-MS/MS; liquid chromatography/tandem mass spectrometry; OPT-BR4; optimized-media-grown BR4; ID-BR4; ideal-media-grown BR4; PQS; Pseudomonas quinolone signal; QS; quorum sensing; RSM; response surface methodology; A

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Structural and biochemical characterization of FabK from Thermotoga maritima

Keywords: FabK; Enoyl-acyl carrier protein (ACP) reductase; Crystal structure; Biochemical characterization; FabK; Enoyl-ACP reductase II; ENR; Enoyl-ACP reductase; FMN; Flavin mononucleotide; NADP; Nicotinamide adenine dinucleotide phosphate; PDB; Protein Data Ban

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Crystal structure of LysK, an enzyme catalyzing the last step of lysine biosynthesis in Thermus thermophilus, in complex with lysine: Insight into the mechanism for recognition of the amino-group carrier protein, LysW

Keywords: M20 metallopeptidase; LysK; Amino-group carrier protein; Crystal structure; Thermus thermophilus; AAA; α-aminoadipate; PDB; Protein Data Bank; r.m.s.d.; root mean square deviation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Flaviviridae viruses use a common molecular mechanism to escape nucleoside analogue inhibitors

Keywords: Flaviviridae; Virus; Polymerase; Analogue; Interrogating; Water; CMA; 2'-C-methyladenosine; CMA-TP; 2'-C-methyladenosine Triphosphate; CPUs; Computer-Processing Units; HCV; Hepatitis C Virus; JEV; Japanese Encephalitis Virus; NTP; Nucleoside Triphosphate;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Microfluidic-based G-quadruplex ligand displacement assay for alkaloid anticancer drug screening

Keywords: G4; G-quadruplex; CD; circular dichroism; CL; chemiluminescence; MD; molecular dynamics; SAU; sanguinarine; BER; berberine; CHE; chelerythrine; MAT; matrine; LIG; ligustrazine; PMT; photomultiplier tube; PME; Particle mesh Ewald method; GAFF; general AMBE

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Usefulness of the ElliPro epitope predictor program in defining the repertoire of HLA-ABC eplets

Keywords: CDR; Complementarity Determining Region; ElliPro; derived from Ellipsoid and Protrusion; HLA; Human Leukocyte Antigen; PDB; Protein Database; HLA epitope; Antibody-verified epitope; Eplet; Epitope registry;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Pharmacophore searching: A potential solution for correcting unknown ligands (UNK) labelling errors in Protein Data Bank (PDB'S)

Keywords: Unknown ligands (UNK); Protein structures; PDB; Coot®; Electron density map; DSV; Catalyst®;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Regression model for predicting pathogenic properties of SOD1 mutants based on the analysis of conformational stability and conservation of hydrogen bonds

Keywords: ALS; amyotrophic lateral sclerosis; EN; elastic-network models; MD; molecular-dynamics simulations; PDB; protein data bank; WT; wild-type; ALS; SOD1; Elastic network models; Hydrogen bonds; Protein stability; Regression model; Patient survival time;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Homology modeling and molecular dynamics simulation of the HIF2α degradation-related HIF2α-VHL complex

Keywords: HIF2α; hypoxia-inducible factor 2α; VHL; Von Hippel-Lindau; pVHL; von Hippel Lindau tumor suppressor protein; CODD; C-terminal oxygen-dependent degradation domain; 3D; three-dimensional; ARNT; aryl hydrocarbon receptor nuclear translocator; HRE; hypox

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of amino acids in antigen-binding site of class II HLA proteins independently associated with hepatitis B vaccine response

Keywords: HBV; hepatitis B virus; anti-HBs; antibody to hepatitis B surface antigen; HBsAg; hepatitis B surface antigen; LD; linkage disequilibrium; PDB; Protein Data Bank; Leu26; leucine at position 26; GGPM; glycine-glycine-proline-methionine; DEAV; aspartic acid

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Design, synthesis, and structure-activity relationships of pyrimido[4,5-b]indole-4-amines as microtubule depolymerizing agents that are effective against multidrug resistant cells

Keywords: NCI; National Cancer Institute; MTAs; microtubule targeting agents; CA-4; combretastatin A-4; DMSO; dimethyl sulfoxide; PDB; Protein Data Bank; Pgp; P-glycoprotein; Rr; relative resistance; NMR; nuclear magnetic resonance; Microtubules; Pyrimido[4,5-b]ind

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

SCOPe: Manual Curation and Artifact Removal in the Structural Classification of Proteins - extended Database

Keywords: SCOPe; Structural Classification of Proteins-extended; SCOP; Structural Classification of Proteins; PDB; Protein Data Bank; CPE; Clostridium perfringens enterotoxin; APA; Anthrax Protective Antigen; structure classification; protein evolution; database;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Databases/Web ServersabYsis: Integrated Antibody Sequence and Structure-Management, Analysis, and Prediction

Keywords: CDR; complementarity-determining region; PDB; Protein Data Bank; IMGT; Immunogenetics Database; EMBL-ENA; European Molecular Biology Laboratory European Nucleotide Archive; antibodies; bioinformatics and computational biology; databases; sequence analysis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

The effects of mutating Tyr9 and Arg15 on the structure, stability, conformational dynamics and mechanism of GSTA3-3

Keywords: CD; circular dichroism; CDNB; 1-chloro-2, 4-dinitrobenzene; EDTA; ethylenediaminetetraacetic acid; GSH; glutathione; GST; glutathione S-transferase; HDX-MS; hydrogen-deuterium exchange mass spectrometry; ITC; isothermal titration calorimetry; PDB; Prote

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Structural insight into mode of binding of Meropenem to CTX-M-15 type β-lactamase

Keywords: PBPs; penicillin binding proteins; IPTG; isopropyl-β-d-1-thiogalactopyranoside; PDB; protein data bank; RFI; relative fluorescence intensity; CD; circular dichroism; Antibiotic resistance; Beta-lactamase; Meropenem; Fluorescence quenching; Molecular dock

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Computational prediction of the effects of non-synonymous single nucleotide polymorphisms in the human Quinone Oxidoreductase 1 (NQO1)

Keywords: SNP; Single nucleotide polymorphisms; nsSNPs; Non-synonymous SNPs; NQO1; NAD(P)H Quinone Oxidoreductase 1; SIFT; Sorting Intolerant from Tolerant; PolyPhen; phenotype polymorphism; ROVEAN; Protein Variation Effect Analyzer; PDB; Protein Data Bank; GDT; gl

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Compound heterozygous KCNQ1 mutations (A300T/P535T) in a child with sudden unexplained death: Insights into possible molecular mechanisms based on protein modeling

Keywords: aa; amino acid; BWA; Burrows-Wheeler aligner; CaM; calmodulin; CPR; cardiopulmonary resuscitation; DNA; deoxyribonucleic acid; ECG; electrocardiogram; GOF; gain of function; KCNE1; potassium voltage-gated channel subfamily E member 1; Kv7.1; voltage-gated

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Genome-wide identification, cloning and characterization of SNARE genes in bread wheat (Triticum aestivum L.) and their response to leaf rust

Keywords: SNARE; soluble N-ethylmaleimide sensitive factor adaptor protein; Receptors TMD; Trans-membrane domain; PR; Pathogenesis-related; qRT-PCR; quantitative Real Time PCR; CDD; Conserved Domain Database; HMM; Hidden Markov Model; MSA; Multiple sequence alignme

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Structural Insights into BAF47 and BAF155 Complex Formation

Keywords: ESC; embryonic stem cell; RPT1; Repeat 1; ITC; isothermal titration calorimetry; GST; glutathione S-transferase; PDB; Protein Data Bank; NMR; nuclear magnetic resonance; HSQC; heteronuclear single quantum coherence; dsDNA; double-stranded DNA; BAF47; BAF1

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Databases/Web Servers3D-NuS: A Web Server for Automated Modeling and Visualization of Non-Canonical 3-Dimensional Nucleic Acid Structures

Keywords: 3D; three-dimensional; PDB; Protein Data Bank; SD; Standard deviation; nucleic acids duplex; triplex; quadruplex; chimera; hairpin;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Research ArticlePharmacophore based 3D-QSAR modeling, virtual screening and docking for identification of potential inhibitors of β-secretase

Keywords: BACE1; β-secretase; AD; Alzheimer's disease; Aβ; amyloid-β; BBB; blood brain barrier; PDB; protein data bank; rmsd; root mean square deviation; IC50; inhibitory concentration; β-secretase; Alzheimer's disease; Pharmacophore; Virtual screening; Doc

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Discorhabdin alkaloids from Antarctic Latrunculia spp. sponges as a new class of cholinesterase inhibitors

Keywords: Acetylcholinesterase inhibitor; Alzheimer's disease; Antarctic sponges; Discorhabdins; Molecular docking; Sponge metabolites; AChE; acetylcholinesterase; BChE; butyrylcholinesterase; eeAChE; electric eel acetylcholinesterase; ESI-MS; electrospray ionisati

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Structural Characterisation Reveals Mechanism of IL-13-Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13Rα1 and IL-13Rα2

Keywords: IL; interleukin; Th2; T helper type 2; PDB; Protein Data Bank; VH; variable heavy; VL; variable light region; CDR; complementary-determining region; FW; framework; PBS; phosphate-buffered saline; HPLC-SEC; high-performance liquid chromatography-size-exc

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Crystal structure and biochemical investigations reveal novel mode of substrate selectivity and illuminate substrate inhibition and allostericity in a subfamily of Xaa-Pro dipeptidases

Keywords: XPD; Xaa-Pro dipeptidase; XPDxc; Xaa-Pro dipeptidase from Xanthomonas campestris; XPDmt; Xaa-Pro dipeptidase from Mycobacterium tuberculosis; XPDll; Xaa-Pro dipeptidase from Lactococcus lactis; AMPPec; aminopeptidase P from Escherichia coli; PDB; Protein

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Characterization, expression, and evolutionary analysis of new TLR3 and TLR5M genes cloned from the spiny eel Mastacembelus armatus

Keywords: Mastacembelus armatus; Spiny eel; Toll-like receptor; TLR3; TLR5M; Vibrio parahaemolyticus; TLR; toll-like receptors; PRR; Pattern-recognition receptor; PAMP; pathogen-associated molecular pattern; LRR; leucine-rich repeat; TM; transmembrane; TIR; Toll/IL

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Importance of 5/6-aryl substitution on the pharmacological profile of 4ʹ-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1ʹ-biphenyl]-2-carboxylic acid derived PPARγ agonists

Keywords: Peroxisome proliferator-activated receptor γ; Pharmacological profile; Coactivator recruitment; Transactivation assay; Molecular modeling; H; helix; LBD; ligand binding domain; PDB; Protein Data Bank; PPAR; peroxisome proliferator-activated receptor; PPR

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Mycobacterium tuberculosis chorismate mutase: A potential target for TB

Keywords: Tuberculosis; Mycobacterium tuberculosis; Chorismate mutase; Inhibitors; BsCM; Bacillus subtilis chorismate mutase; CM; chorismate mutase; DAHP; 3-deoxy-d-arabinoheptulosonate 7-phosphate; EcCM; Escherichia coli chorismate mutase; HIV/AIDS; human Immunode

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Pyrrolizines: Design, synthesis, anticancer evaluation and investigation of the potential mechanism of action

Keywords: ALK1; activin receptor-like kinase; CDCl3; deuterated chloroform; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide; DSV; discovery studio visualizer; DYRK3; dual specificity tyrosine phosphorylation-regulated kinase; CDK2; cyclin-depende

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Studies of CDK 8/19 inhibitors: Discovery of novel and selective CDK8/19 dual inhibitors and elimination of their CYP3A4 time-dependent inhibition potential

Keywords: ADME; absorption, distribution, metabolism, and excretion; AML; acute myelogenous leukemia; AUC; area under the blood concentration time curve; b.i.d.; twice a day; CDK; Cyclin-dependent kinase; CLtotal; clearance; Cmax; maximum drug concentration; CRC; c

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

A Glimpse of Membrane Transport through Structures-Advances in the Structural Biology of the GLUT Glucose Transporters

Keywords: membrane transport; major facilitator superfamily; alternating access; GLUT1; SLC2A; MP; membrane protein; PDB; Protein Data Bank; cryo-EM; electron cryomicroscopy; MFS; major facilitator superfamily; SLC; solute carrier; TM; transmembrane; SP; sugar port

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

MODCSA-CA: A multi objective diversity controlled self adaptive cuckoo algorithm for protein structure prediction

Keywords: MODCSA; multi objective diversity controlled self adaptive; CA; cuckoo algorithm; CS; cuckoo search; PDB; Protein Data Bank; IMMALG; Immune Algorithm; I-PAES; inspired Pareto archived evolutionary strategy; HGA; Hybrid Genetic Algorithm; MODE-P; multi-obj

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه